{"id":"W2519965024","doi":"10.1097/01.hjh.0000501088.36686.4b","title":"MPS 18-02 ENDOTHELIN-1 OVEREXPRESSION PRESERVES ENDOTHELIAL FUNCTION IN MICE WITH VASCULAR SMOOTH MUSCLE CELL-SPECIFIC DELETION OF PPAR-GAMMA","year":2016,"lang":"en","type":"article","venue":"Journal of Hypertension","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Research Canada","funders":"","keywords":"Endocrinology; Internal medicine; Medicine; Vascular smooth muscle; Electrical impedance myography; Endothelin 1; Monocyte; Angiotensin II; Oxidative stress; Mesenteric arteries; Endothelium; Inflammation; Receptor; Vasodilation; Artery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002123432,0.001016122,0.0006038955,0.0007203573,0.0002229093,0.0004629101,0.0004778627,0.0005490073,0.003666124],"category_scores_gemma":[0.0001378768,0.0004645574,0.0005623472,0.0002800011,0.0004496376,0.000354262,0.0002736269,0.001410833,0.00106751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003400612,"about_ca_system_score_gemma":0.0003271601,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005397754,"about_ca_topic_score_gemma":0.0008341646,"domain_scores_codex":[0.9996648,0.00004004812,0.00003965008,0.0000843266,0.00007555939,0.00009557752],"domain_scores_gemma":[0.9994872,0.00003147732,0.0002482408,0.00004355875,0.00002447727,0.0001651303],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005471056,0.0001426864,0.0001483669,0.00003232499,0.00001399031,0.000106165,0.00001907498,0.00004149269,0.9976561,0.00008713992,0.00005528401,0.001150144],"study_design_scores_gemma":[0.0004336478,0.003213784,0.009087815,0.00004157449,0.0001268721,0.0009479163,0.00008678876,0.0007201009,0.9794883,0.0001263029,0.005709929,0.00001692132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937441,0.0006341322,0.00267608,0.0001520662,0.00007877086,0.00005264759,0.001167042,0.000272843,0.001222396],"genre_scores_gemma":[0.9742439,0.001614135,0.004342808,0.0002162213,0.00006760351,0.000250261,0.002895899,0.0002652394,0.01610388],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003666124,"threshold_uncertainty_score":0.01226443,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01882369155439625,"score_gpt":0.2242256792641788,"score_spread":0.2054019877097825,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}