{"id":"W2520021448","doi":"10.7448/ias.19.1.21163","title":"Initiation of antiretroviral therapy before detection of colonic infiltration by HIV reduces viral reservoirs, inflammation and immune activation","year":2016,"lang":"en","type":"article","venue":"Journal of the International AIDS Society","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health; Delaney AIDS Research Enterprise","keywords":"Medicine; Neopterin; Peripheral blood mononuclear cell; Viral load; CD38; Immune system; CD8; Immunology; Gastroenterology; Chemokine; Inflammation; Internal medicine; Human immunodeficiency virus (HIV); Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000294918,0.0001609181,0.0003403276,0.0001152763,0.0001641725,0.0003415577,0.0001120846,0.0001804394,0.002349872],"category_scores_gemma":[0.001062936,0.00007158129,0.0001339292,0.0001664414,0.0001053852,0.0001560737,0.0001203752,0.0002886293,0.0001985288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001343278,"about_ca_system_score_gemma":0.0002264108,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004080111,"about_ca_topic_score_gemma":0.0009453087,"domain_scores_codex":[0.9998358,0.00006097865,0.00001408945,0.00002668308,0.00003046245,0.00003187351],"domain_scores_gemma":[0.9993767,0.0002459661,0.0002158384,0.00003484402,0.00004435578,0.00008235053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01161014,0.001495823,0.6743814,0.0008346137,0.0003389468,0.000658894,0.0004473108,0.0003011303,0.0725,0.0001661921,0.001230416,0.2360353],"study_design_scores_gemma":[0.0001791065,0.006624934,0.9803349,0.0001959866,0.0001347919,0.001083834,0.0002661057,0.0003633772,0.007960699,0.0001037611,0.002743118,0.000009325697],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961981,0.002495848,0.0001738335,0.00009198944,0.00002339489,0.00001756131,0.0001482096,0.00001583195,0.0008351809],"genre_scores_gemma":[0.9985042,0.0006293121,0.0003585967,0.00005999958,0.00002750449,0.00001500197,0.000149493,0.000002818294,0.0002531075],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002349872,"threshold_uncertainty_score":0.007861137,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009959710711667364,"score_gpt":0.2515644720498068,"score_spread":0.2416047613381394,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}