{"id":"W2520142124","doi":"10.1111/hiv.12389","title":"Reference curves for <scp>CD</scp>4 T‐cell count response to combination antiretroviral therapy in <scp>HIV</scp>‐1‐infected treatment‐naïve patients","year":2016,"lang":"en","type":"article","venue":"HIV Medicine","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Instituto de Salud Carlos III; Medical Research Council; National Institutes of Health; Augustinus Fonden; Fundación Para La Innovación Y La Prospectiva En Salud En España; Agence Nationale de Recherches sur le Sida et les Hépatites Virales; European Commission; Gilead Sciences; Styrelsen för Internationellt Utvecklingssamarbete; Ministerio de Sanidad, Servicios Sociales e Igualdad; Novartis; Seventh Framework Programme; AbbVie; Merck; Bristol-Myers Squibb Foundation","keywords":"Medicine; Antiretroviral therapy; Human immunodeficiency virus (HIV); Viral load; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005196968,0.000347814,0.000537401,0.0003865966,0.0001622816,0.000009741025,0.0002381212,0.0002155485,0.000116139],"category_scores_gemma":[0.002168661,0.000204674,0.00007629475,0.0003194829,0.0002352625,0.0001192031,0.00004436956,0.0001524314,0.001268239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003539885,"about_ca_system_score_gemma":0.000166224,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001556235,"about_ca_topic_score_gemma":0.00008088277,"domain_scores_codex":[0.9975529,0.0005609368,0.0004362319,0.0005380532,0.0001580881,0.0007537747],"domain_scores_gemma":[0.9958917,0.003115364,0.0001550244,0.0004273916,0.0002834175,0.000127053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001857267,0.003163787,0.3589943,0.00007829031,0.0003220077,0.00005097448,0.003007474,4.791514e-7,0.4199436,0.0001679601,0.188292,0.02412187],"study_design_scores_gemma":[0.04435027,0.02312274,0.5865763,0.0005954742,0.00006546507,0.000007240737,0.0004094304,0.000002126791,0.05914557,0.00008862947,0.2855347,0.0001021466],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915463,0.002724057,0.0001279782,0.001396638,0.0002778903,0.001775766,0.0006300046,0.00008078625,0.001440556],"genre_scores_gemma":[0.9725729,0.002390669,0.00003388837,0.0003335933,0.0000378589,0.0004441272,0.001593081,0.00003256436,0.0225613],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.360798,"threshold_uncertainty_score":0.9995094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02368243899903601,"score_gpt":0.2851086291025811,"score_spread":0.2614261901035451,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}