{"id":"W2520565432","doi":"10.1021/es303289n","title":"Accumulation and Biotransformation of BDE-47 by Zebrafish Larvae and Teratogenicity and Expression of Genes along the Hypothalamus–Pituitary–Thyroid Axis","year":2012,"lang":"en","type":"article","venue":"Environmental Science & Technology","topic":"Birth, Development, and Health","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Biotransformation; Hypothalamus; Zebrafish; Hypothalamic–pituitary–thyroid axis; Thyroid; Pituitary gland; Endocrinology; Biology; Internal medicine; Larva; Gene; Chemistry; Thyroid hormones; Medicine; Genetics; Ecology; Biochemistry; Hormone; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008923941,0.0004262676,0.0002015133,0.000241308,0.0001467938,0.0001847391,0.0001053658,0.0002406536,0.001163555],"category_scores_gemma":[0.00009266196,0.0002325544,0.0003429508,0.0001353304,0.0002356282,0.0001487519,0.0001594038,0.0004138322,0.0002581019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005771847,"about_ca_system_score_gemma":0.0004101795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00510966,"about_ca_topic_score_gemma":0.009185583,"domain_scores_codex":[0.9999094,0.000007315035,0.00001005324,0.00002414557,0.00002622032,0.00002287],"domain_scores_gemma":[0.9999192,0.00001060685,0.00002973414,0.00000606465,0.00001817899,0.0000162711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001061775,0.000006493249,0.0003285642,0.00001582761,0.000003340561,0.00002821625,0.00001528306,0.00003186199,0.9991006,0.0000195609,0.00001435572,0.0003297948],"study_design_scores_gemma":[0.00001145461,0.0006422537,0.01646267,0.000007833299,0.00002524745,0.0000836145,0.00005688055,0.0002375162,0.9813423,0.00002243256,0.001099654,0.000008073604],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961486,0.0007515971,0.0007106938,0.00006995798,0.00001972986,0.00002816574,0.0008195035,0.00003062336,0.00142116],"genre_scores_gemma":[0.9872235,0.001237537,0.001489311,0.00007693651,0.000007613861,0.0000843694,0.001246644,0.00002026664,0.008613844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00510966,"threshold_uncertainty_score":0.01015985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01422048647433585,"score_gpt":0.2548233322918504,"score_spread":0.2406028458175146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}