{"id":"W2520582931","doi":"10.3892/or.2016.5085","title":"MPS1 kinase as a potential therapeutic target in medulloblastoma","year":2016,"lang":"en","type":"article","venue":"Oncology Reports","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"University of Colorado School of Medicine, Anschutz Medical Campus; National Institute of Neurological Disorders and Stroke; National Cancer Institute; National Institutes of Health; Morgan Adams Foundation; Childhood Brain Tumor Foundation","keywords":"Medulloblastoma; Cancer research; Biology; Cell cycle; Mitosis; Oncogene; Clonogenic assay; Cancer; Apoptosis; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001188701,0.0002943251,0.0003508329,0.0003439816,0.0001873903,0.0003617354,0.0001951362,0.0002408403,0.0009870746],"category_scores_gemma":[0.00007285245,0.00009115289,0.0001944166,0.0001881539,0.0001791132,0.000211853,0.0001791909,0.000589543,0.0002660407],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005497196,"about_ca_system_score_gemma":0.0003281532,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006869229,"about_ca_topic_score_gemma":0.002345304,"domain_scores_codex":[0.9999578,0.000008851848,0.000003285323,0.000007750103,0.00001063096,0.00001159862],"domain_scores_gemma":[0.9999784,0.000004113077,0.000006835018,0.000001579582,0.000002937073,0.000006069372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001188124,0.0003693315,0.001394221,0.00112434,0.00007476381,0.001069688,0.0001081434,0.001738179,0.896988,0.002121117,0.002135911,0.09168831],"study_design_scores_gemma":[0.0006081945,0.004803295,0.01656745,0.0001912196,0.000299581,0.004106803,0.0001918549,0.004974945,0.8408448,0.001425406,0.1259416,0.00004484881],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8364824,0.1438301,0.004796711,0.00216696,0.0002895205,0.0002076724,0.0006342882,0.0003618267,0.01123054],"genre_scores_gemma":[0.9529713,0.04102496,0.002311592,0.000197535,0.00006445272,0.00006059186,0.0003764766,0.00001733445,0.002975836],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009870746,"threshold_uncertainty_score":0.003988504,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00503662893895932,"score_gpt":0.2564440656181637,"score_spread":0.2514074366792044,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}