{"id":"W2521085149","doi":"10.1016/s0168-8278(15)31090-4","title":"P1353 : A single tablet regimen of ledipasvir/sofosbuvir for 12 weeks in HCV genotype 1 or 4 infected patients with HIV-1 co-infection : The phase 3 ION-4 study","year":2015,"lang":"en","type":"article","venue":"Journal of Hepatology","topic":"Hepatitis C virus research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Ledipasvir; Sofosbuvir; Regimen; Genotype; Medicine; Human immunodeficiency virus (HIV); Virology; Internal medicine; Gastroenterology; Hepatitis C virus; Virus; Biology; Ribavirin; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001109755,0.001939572,0.002654959,0.0005445583,0.0004259128,0.001091452,0.001256359,0.001489212,0.004438541],"category_scores_gemma":[0.0008727857,0.0008473215,0.002001623,0.0004534582,0.001103347,0.00136778,0.0004176339,0.003457067,0.001188801],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009040996,"about_ca_system_score_gemma":0.001669065,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002655683,"about_ca_topic_score_gemma":0.004817981,"domain_scores_codex":[0.9995961,0.0001769947,0.00001651613,0.00006363205,0.00003390894,0.0001127535],"domain_scores_gemma":[0.9996388,0.00005305928,0.00005700551,0.000030532,0.00001903003,0.0002015414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8633341,0.0308527,0.002225062,0.0006488486,0.001473485,0.0001684581,0.0001674756,0.001616125,0.01785717,0.0002211457,0.002760879,0.07867463],"study_design_scores_gemma":[0.7798581,0.2090101,0.006451561,0.00003478473,0.0005414159,0.0001266536,0.0000646324,0.001117497,0.001336825,0.0001595713,0.001243801,0.00005496859],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935481,0.001983807,0.0004544165,0.0004284522,0.0001686302,0.0009428205,0.0008748214,0.0002680692,0.001330781],"genre_scores_gemma":[0.9901493,0.001987713,0.001685175,0.0007992868,0.0001497722,0.000972189,0.001308737,0.00005954481,0.002888244],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004438541,"threshold_uncertainty_score":0.01484841,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07751909082488675,"score_gpt":0.3774465576547296,"score_spread":0.2999274668298428,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}