{"id":"W2521163995","doi":"10.1093/neuonc/now200","title":"Old chemotherapy makes a comeback: dual alkylator therapy for pediatric high-grade glioma","year":2016,"lang":"en","type":"letter","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Chemotherapy; Medicine; Glioma; Internal medicine; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000970086,0.0005364839,0.0008358668,0.0004834109,0.001606059,0.001652613,0.0008079531,0.01445174,0.001784851],"category_scores_gemma":[0.009079128,0.000322641,0.00083202,0.0004360209,0.001220916,0.002293405,0.0007617354,0.01556047,0.001089952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002839219,"about_ca_system_score_gemma":0.001671888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002123467,"about_ca_topic_score_gemma":0.005585106,"domain_scores_codex":[0.9991112,0.000288988,0.0001426606,0.00009124169,0.000218188,0.0001476903],"domain_scores_gemma":[0.9980002,0.000963277,0.0002337948,0.00006634047,0.0002071812,0.0005292622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003060154,0.0002562354,0.00980829,0.0002924657,0.0001014939,0.2339003,0.0005056146,0.001083333,0.001646926,0.008547736,0.6713325,0.07221916],"study_design_scores_gemma":[0.000411181,0.0007032385,0.007662115,0.0006534815,0.0002073743,0.3257229,0.001275527,0.00298764,0.001723571,0.03482245,0.6236858,0.0001447355],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.007718665,0.005567013,0.0004136369,0.9702011,0.0118285,0.00001719219,0.00005329414,0.00003390222,0.004166805],"genre_scores_gemma":[0.1005705,0.0142621,0.00201663,0.7588773,0.1141291,0.00005589993,0.0001172387,0.00007336011,0.009897842],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.01445174,"threshold_uncertainty_score":0.02060008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02500682719234743,"score_gpt":0.2979366192287641,"score_spread":0.2729297920364167,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}