{"id":"W2521489627","doi":"10.1042/cs20171620","title":"Small vessels, dementia and chronic diseases – molecular mechanisms and pathophysiology","year":2018,"lang":"en","type":"article","venue":"Clinical Science","topic":"Neurological Disease Mechanisms and Treatments","field":"Neuroscience","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Discovery Centre","funders":"National Institute on Aging; Medical Research Council; Dementias Platform UK; Lundbeckfonden; Fondation Leducq; Novo Nordisk Fonden; Academy of Medical Sciences; National Centre for the Replacement, Refinement and Reduction of Animals in Research; Rosetrees Trust; British Heart Foundation; National Institute of Neurological Disorders and Stroke; National Institute for Health and Care Research; Alzheimer's Society","keywords":"Dementia; Scope (computer science); Disease; Vascular dementia; Medicine; Psychological intervention; Stroke (engine); Translational research; Neuroscience; Psychology; Intensive care medicine; Pathology; Computer science; Psychiatry; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002560109,0.0001486944,0.0001938775,0.00004215666,0.0004116964,0.0000939169,0.0003363685,0.00005832212,0.00006652891],"category_scores_gemma":[0.0009628421,0.0001077168,0.00004843678,0.0002782206,0.002513225,0.0001375538,0.0005128485,0.00009983626,0.00005821837],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001129375,"about_ca_system_score_gemma":0.00008337288,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003380999,"about_ca_topic_score_gemma":0.000001430369,"domain_scores_codex":[0.9979229,0.0001609411,0.0002356351,0.001040861,0.0002143216,0.0004253156],"domain_scores_gemma":[0.998877,0.0002424477,0.00008140293,0.0002910464,0.00003683187,0.0004712244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00004130366,0.0003405217,0.001155617,0.00001010416,0.000004832669,0.0001468424,0.000007889085,9.163783e-7,0.9041128,0.06893256,0.00001118271,0.02523541],"study_design_scores_gemma":[0.001916741,0.006785044,0.1564362,0.00002725764,0.0001800621,0.00002846763,0.000009781637,0.004403029,0.2819648,0.547106,0.0005849129,0.0005577017],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969442,0.0002346261,0.001648045,0.0002844403,0.0003786299,0.0002047241,0.00001610356,0.00006192351,0.0002272864],"genre_scores_gemma":[0.9959205,0.0001903101,0.0007281119,0.003049524,0.00006964632,0.00001571398,5.717174e-7,0.00000768366,0.00001794394],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.622148,"threshold_uncertainty_score":0.9260081,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05436997952698978,"score_gpt":0.3296237987209714,"score_spread":0.2752538191939816,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}