{"id":"W2521502802","doi":"10.14309/00000434-201510001-01841","title":"A Randomized, Double-Blind, Placebo-Controlled Trial of Ozanimod, an Oral S1P Receptor Modulator, in Moderate to Severe Ulcerative Colitis: Results of the Maintenance Period of the TOUCHSTONE Study","year":2015,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Robarts Clinical Trials; Western University","funders":"","keywords":"Medicine; Placebo; Internal medicine; Tolerability; Ulcerative colitis; Gastroenterology; Clinical trial; Maintenance therapy; Randomized controlled trial; Adverse effect; Chemotherapy; Pathology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001474378,0.001072471,0.003112803,0.0002675514,0.0003851113,0.0007457802,0.0008258939,0.001618605,0.0051636],"category_scores_gemma":[0.001449516,0.0006443071,0.001101972,0.0002737452,0.00108158,0.0006921006,0.0003395065,0.001794654,0.0006556554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003571316,"about_ca_system_score_gemma":0.0007844862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005626499,"about_ca_topic_score_gemma":0.001109393,"domain_scores_codex":[0.9994386,0.0003148802,0.00004184891,0.00009043237,0.0000453241,0.00006893833],"domain_scores_gemma":[0.9989328,0.0002977482,0.0002379933,0.00009511159,0.0000578301,0.0003784088],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9902903,0.002856584,0.0003110461,0.0001906865,0.0002117716,0.00001832866,0.00002391796,0.00005654338,0.001858589,0.00002600602,0.0001540971,0.004002035],"study_design_scores_gemma":[0.9347367,0.06284475,0.001649262,0.00001306522,0.0001812139,0.00001584282,0.00001091925,0.0001376076,0.0002093785,0.00002591247,0.000168766,0.000006651447],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955038,0.001746689,0.000227923,0.0001912071,0.0002330119,0.00116134,0.0002888119,0.00004296734,0.0006042819],"genre_scores_gemma":[0.9932166,0.001390783,0.000699205,0.0005143307,0.0003260295,0.001662471,0.000574858,0.00001004644,0.001605611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0051636,"threshold_uncertainty_score":0.01727402,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03177384796326568,"score_gpt":0.3072183691591573,"score_spread":0.2754445211958917,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}