{"id":"W2521536129","doi":"10.1128/aac.01357-16","title":"Potential Use of Dimethyl Sulfoxide in Treatment of Infections Caused by Pseudomonas aeruginosa","year":2016,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"China Postdoctoral Science Foundation; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China; Government of Canada; Manitoba Health Research Council","keywords":"Pyocyanin; Pseudomonas aeruginosa; Biofilm; Microbiology; Dimethyl sulfoxide; Quorum sensing; Virulence; Virulence factor; Autoinducer; In vivo; Chemistry; Pathogen; Biology; Bacteria; Biochemistry; Organic chemistry; Biotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002900698,0.0003147373,0.0002731664,0.0004029008,0.0002488794,0.0001899976,0.0002652551,0.0003111206,0.001012341],"category_scores_gemma":[0.0002500759,0.00007255662,0.0002283207,0.0001478044,0.0001613063,0.0001941832,0.0002423467,0.0002674484,0.0001920846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001358711,"about_ca_system_score_gemma":0.0001823059,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000209986,"about_ca_topic_score_gemma":0.0004707243,"domain_scores_codex":[0.9998728,0.00004964639,0.00001456025,0.00001546017,0.00003248074,0.00001496997],"domain_scores_gemma":[0.9998816,0.00002880092,0.00003392743,0.000007447603,0.00002204502,0.00002609994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002219485,0.000600056,0.001082293,0.001169541,0.00007046387,0.0007979275,0.00008875847,0.0003122337,0.9101095,0.0004877509,0.001053676,0.08200846],"study_design_scores_gemma":[0.000241528,0.008276013,0.005255707,0.0001047629,0.0002395826,0.001547036,0.0001118519,0.001063186,0.9431208,0.0002917146,0.03972286,0.00002490679],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8732365,0.1110136,0.006703648,0.001431529,0.0007248914,0.000174399,0.0003676352,0.0001766535,0.006171177],"genre_scores_gemma":[0.9788689,0.01583291,0.003167844,0.0001723616,0.0001718346,0.00005271664,0.00012784,0.00001009638,0.001595357],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001012341,"threshold_uncertainty_score":0.003386676,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01044182898986112,"score_gpt":0.2318110991977049,"score_spread":0.2213692702078438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}