{"id":"W2521629096","doi":"10.1016/j.atherosclerosis.2016.07.036","title":"Paraoxonase 1 (PON1) maintains cellular cholesterol homeostasis via the regulation of cholesterol efflux","year":2016,"lang":"en","type":"article","venue":"Atherosclerosis","topic":"Paraoxonase enzyme and polymorphisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôpital Fleurimont","funders":"","keywords":"PON1; Paraoxonase; Efflux; Cholesterol; Chemistry; Homeostasis; Reverse cholesterol transport; Biochemistry; Endocrinology; Biology; Lipoprotein; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003851,0.0003417338,0.0004382089,0.0003728914,0.000271537,0.0006307747,0.0003357554,0.000362046,0.001274513],"category_scores_gemma":[0.0008359019,0.0001630045,0.0001921954,0.0003545969,0.0003288162,0.0003301864,0.000338653,0.0006689675,0.0003023911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003033269,"about_ca_system_score_gemma":0.0003250765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009437038,"about_ca_topic_score_gemma":0.0006185306,"domain_scores_codex":[0.9997513,0.00006884504,0.00001337776,0.0000648513,0.00006582867,0.00003585291],"domain_scores_gemma":[0.999638,0.00007705545,0.0001390762,0.00003382767,0.00006954506,0.00004248671],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003474721,0.0002152275,0.06089829,0.0004643431,0.0002366747,0.0008380505,0.0003273546,0.0004114419,0.8637067,0.004263709,0.001013609,0.06414988],"study_design_scores_gemma":[0.0002726836,0.001508009,0.3715695,0.0001190883,0.0004336372,0.005781631,0.0004354164,0.005098762,0.5888391,0.00555153,0.02031711,0.00007361527],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9796422,0.01010175,0.00701856,0.0007355798,0.00007080039,0.00003275918,0.0004167278,0.0001072308,0.001874501],"genre_scores_gemma":[0.9927924,0.00244609,0.002112906,0.00006460579,0.00003292115,0.00001645178,0.0001777531,0.00001331061,0.002343545],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001274513,"threshold_uncertainty_score":0.004263699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01373667436304772,"score_gpt":0.2244133277883912,"score_spread":0.2106766534253434,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}