{"id":"W2521817506","doi":"10.1182/blood.v104.11.697.697","title":"High Cyclin D1 Expression Is Associated with Increased Proliferation Rate and Decreased Survival in Mantle Cell Lymphoma (MCL) and Is Caused by Genomic Deletions and Mutations that Enhance Stability of Cyclin D1 mRNA.","year":2004,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; University of Alberta","funders":"","keywords":"Cyclin D1; Biology; Molecular biology; Mantle cell lymphoma; Cell growth; Gene; Untranslated region; Gene expression; Cyclin; Cancer research; Cyclin D; Messenger RNA; Genetics; Cell cycle; Lymphoma; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002071354,0.0001786101,0.0001985057,0.0008857108,0.000192183,0.0002858767,0.0001134429,0.0002480068,0.001184137],"category_scores_gemma":[0.0005402893,0.0002296245,0.0001182951,0.0004890661,0.0003056641,0.0001332247,0.0002023487,0.0003420925,0.0002199508],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001511194,"about_ca_system_score_gemma":0.00006879179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003081256,"about_ca_topic_score_gemma":0.0003936754,"domain_scores_codex":[0.9998388,0.00003320766,0.00001655999,0.00004338322,0.00003699004,0.00003105815],"domain_scores_gemma":[0.9993265,0.0001432736,0.0003540174,0.0000313951,0.0000377179,0.0001070702],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001841221,0.00007925672,0.5416558,0.00006548542,0.00007457596,0.001085655,0.0001191415,0.000167096,0.44967,0.00005457311,0.0001653035,0.005021986],"study_design_scores_gemma":[0.0000337844,0.0002894666,0.9781959,0.000003875737,0.00003419144,0.003465334,0.00006163493,0.0002898721,0.01727824,0.00006314478,0.0002787917,0.000005708538],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995356,0.0001630649,0.0001335541,0.00001059025,0.000001096118,0.00000179641,0.00006219398,0.000007067999,0.00008503893],"genre_scores_gemma":[0.9994963,0.00006769963,0.0001741039,0.00001061158,0.000006081194,0.000003562234,0.0001496437,0.000003490045,0.00008854504],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001184137,"threshold_uncertainty_score":0.003961325,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01003671946747501,"score_gpt":0.2285625115292728,"score_spread":0.2185257920617978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}