{"id":"W2521870844","doi":"10.1182/blood.v116.21.3648.3648","title":"Modeling Human T Cell Acute Lymphoblastic Leukemia In Vitro and In Vivo with LMO2.","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"T-cell and Retrovirus Studies","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval; University of Toronto","funders":"","keywords":"Biology; Severe combined immunodeficiency; Progenitor cell; Haematopoiesis; Cancer research; Stem cell; T cell; CD8; In vivo; Cell culture; Leukemia; Genetic enhancement; Immunology; Molecular biology; Cell biology; Gene; Genetics; Antigen; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006834816,0.0001327379,0.0002122637,0.0001005625,0.0001041386,0.000007952623,0.00008607875,0.000161981,0.00002784977],"category_scores_gemma":[0.0000058918,0.00009863652,0.0000193765,0.00007473763,0.0001222388,0.00003729116,0.00007069632,0.000310089,0.00002162468],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001995585,"about_ca_system_score_gemma":0.00004750099,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005425453,"about_ca_topic_score_gemma":0.001597921,"domain_scores_codex":[0.9993085,0.00002587524,0.0001518274,0.0002237334,0.00001746722,0.0002726243],"domain_scores_gemma":[0.9997922,0.00002853853,0.00002847491,0.0001235595,0.00001387245,0.00001341612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001075554,0.0001221458,0.005125185,0.0000133064,0.00004816283,0.00002776613,0.0004296565,0.00005894755,0.9939728,0.00002637065,0.00001399828,0.00005411818],"study_design_scores_gemma":[0.008940446,0.0001846697,0.001898359,0.00003588606,0.0001177043,0.0001096445,0.0002651378,0.0002350375,0.987525,0.0001018089,0.000295136,0.0002911391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974134,0.0007753233,0.00001180402,0.00001391871,0.0001102696,0.00009338598,0.00001018435,0.00002418052,0.001547563],"genre_scores_gemma":[0.9989437,0.00005737775,0.00009964901,0.00003144484,0.000017776,0.00001303825,0.000006110628,0.00001182502,0.0008190041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008832891,"threshold_uncertainty_score":0.4022281,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005501561584467737,"score_gpt":0.1969258262815446,"score_spread":0.1914242646970769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}