{"id":"W2521919853","doi":"10.1136/gutjnl-2016-311629","title":"Ex vivo study of human visceral nociceptors","year":2016,"lang":"en","type":"article","venue":"Gut","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Canadian Institutes of Health Research; Crohn's and Colitis Foundation of Canada; Biotechnology and Biological Sciences Research Council; Crohn's and Colitis Foundation; Wellcome Trust; Bowel and Cancer Research","keywords":"Nociceptor; Bradykinin; Transient receptor potential channel; Nociception; TRPV4; Tegaserod; Medicine; Visceral pain; Electrophysiology; Pharmacology; Receptor; Chemistry; Anesthesia; Internal medicine; Neuroscience; Irritable bowel syndrome; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004423559,0.0003040626,0.0002487779,0.0001383457,0.0001216012,0.0002181482,0.0001905029,0.0002586253,0.004915753],"category_scores_gemma":[0.0002443248,0.0001184014,0.000200578,0.0001223583,0.0002235775,0.0003298928,0.0002665963,0.0004130451,0.0008187473],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005750088,"about_ca_system_score_gemma":0.00007621265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009401322,"about_ca_topic_score_gemma":0.0001080319,"domain_scores_codex":[0.9998438,0.00003516663,0.000012951,0.00004454662,0.00003699736,0.00002649337],"domain_scores_gemma":[0.9999043,0.00003473822,0.00001428964,0.00001680125,0.0000164115,0.00001337508],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002398969,0.00004814194,0.0002258806,0.0001092822,0.00000646708,0.0001154371,0.00002241103,0.00006008848,0.9960805,0.0000850198,0.0000759781,0.00293107],"study_design_scores_gemma":[0.0001288899,0.008473302,0.02589844,0.00009009367,0.000102428,0.004022721,0.0002801876,0.002756049,0.9419883,0.000319724,0.01592382,0.00001615848],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9290298,0.0120378,0.0511382,0.0002896225,0.0002584857,0.0002762451,0.001009114,0.0001382734,0.00582253],"genre_scores_gemma":[0.9639809,0.006360014,0.02110877,0.0002581678,0.0001283254,0.0003727642,0.001628931,0.00002849937,0.006133553],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004915753,"threshold_uncertainty_score":0.0164448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02540927975056145,"score_gpt":0.3201515900384742,"score_spread":0.2947423102879128,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}