{"id":"W2521919853","doi":"10.1136/gutjnl-2016-311629","title":"Ex vivo study of human visceral nociceptors","year":2016,"lang":"en","type":"article","venue":"Gut","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Canadian Institutes of Health Research; Crohn's and Colitis Foundation of Canada; Biotechnology and Biological Sciences Research Council; Crohn's and Colitis Foundation; Wellcome Trust; Bowel and Cancer Research","keywords":"Nociceptor; Bradykinin; Transient receptor potential channel; Nociception; TRPV4; Tegaserod; Medicine; Visceral pain; Electrophysiology; Pharmacology; Receptor; Chemistry; Anesthesia; Internal medicine; Neuroscience; Irritable bowel syndrome; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006491445,0.00006421094,0.0001456958,0.00003678254,0.00002803498,0.000001734179,0.00003636276,0.00002515196,0.0006888237],"category_scores_gemma":[0.00001151184,0.00003607673,0.00003584983,0.00003584648,0.00001381362,0.00002147346,0.00001837004,0.00002204095,0.00009725216],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002664422,"about_ca_system_score_gemma":0.000009925986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001063171,"about_ca_topic_score_gemma":0.000026723,"domain_scores_codex":[0.9995164,0.00001954724,0.0001101396,0.0001131372,0.0001372061,0.0001035314],"domain_scores_gemma":[0.9996868,0.00001388349,0.00003707829,0.0001840184,0.00002542231,0.00005277502],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001114636,0.003008146,0.2957711,0.0000299605,0.0003607907,0.0001099112,0.001921048,9.281707e-8,0.6829244,0.0009754134,0.002726694,0.01206099],"study_design_scores_gemma":[0.02584301,0.01193248,0.8329939,0.0003047326,0.0004987391,0.00001838887,0.0022783,0.000005573522,0.1197505,0.001638619,0.004403425,0.0003323335],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945872,0.00001257297,0.00003949125,0.000082568,0.00007081429,0.0002221114,0.000002951683,0.00002350982,0.00495871],"genre_scores_gemma":[0.9918047,0.000002017097,0.0001066995,0.00004747702,0.00005975749,0.000008340022,0.000001099335,0.000009177857,0.007960697],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5631739,"threshold_uncertainty_score":0.7542136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02540927975056145,"score_gpt":0.3201515900384742,"score_spread":0.2947423102879128,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}