{"id":"W2521940310","doi":"10.1212/wnl.86.16_supplement.p2.341","title":"An Update on STEADY-PD III: A Phase 3 Study of Isradipine as a Disease Modifying Agent in Patients with Early Parkinson’s Disease (P2.341)","year":2016,"lang":"en","type":"article","venue":"Neurology","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Isradipine; Parkinson's disease; Disease; Medicine; Internal medicine; Receptor","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004816815,0.001042996,0.002521571,0.001122758,0.0006071306,0.002093264,0.002511713,0.003836556,0.003550263],"category_scores_gemma":[0.003802471,0.000425842,0.001821796,0.001175413,0.0004616486,0.001380062,0.0005987934,0.004392001,0.002515899],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001033547,"about_ca_system_score_gemma":0.002147552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002003516,"about_ca_topic_score_gemma":0.007917799,"domain_scores_codex":[0.9989628,0.0003745762,0.0001609349,0.00008517666,0.0003273817,0.00008926079],"domain_scores_gemma":[0.996849,0.0009755223,0.0005205223,0.00009029359,0.001041008,0.0005236816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.004790443,0.0007566891,0.001265331,0.006954241,0.0005519168,0.0005447494,0.0001274627,0.0003694872,0.00599557,0.00145548,0.1850573,0.7921312],"study_design_scores_gemma":[0.01190652,0.007019652,0.009963268,0.004312477,0.001878824,0.00119295,0.00007608432,0.0005960328,0.001786407,0.001274157,0.9599121,0.00008164089],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.02650853,0.8051007,0.007744888,0.07973307,0.0157138,0.003019709,0.006858903,0.001011045,0.05430937],"genre_scores_gemma":[0.06629915,0.7236103,0.02151993,0.110729,0.01864081,0.005352431,0.01450601,0.000383503,0.0389589],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004816815,"threshold_uncertainty_score":0.02547407,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01698971553330803,"score_gpt":0.2793137604377159,"score_spread":0.2623240449044079,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}