{"id":"W2521962771","doi":"10.1182/blood.v108.11.193.193","title":"Factor V Binding to Multimerin 1: Modulation by Factor V Activation and Binding Sites in the Factor V C1 and C2 Domains.","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Factor V; Binding site; Plasma protein binding; C2 domain; Biophysics; Factor IXa; Chemistry; Factor X; Tissue factor; Binding domain; Prothrombinase; Factor H; Thrombin; Biology; Platelet; Biochemistry; Complement system; Coagulation; Immunology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002219613,0.0003381417,0.0001474672,0.0001608064,0.0001611695,0.0002583865,0.0003894644,0.0003383553,0.002611497],"category_scores_gemma":[0.0003823932,0.0001819562,0.0001750208,0.0001562588,0.0001863954,0.00016156,0.0001515122,0.0003775911,0.0004579747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000622812,"about_ca_system_score_gemma":0.0001483147,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002851923,"about_ca_topic_score_gemma":0.002134117,"domain_scores_codex":[0.9998102,0.00004719796,0.00000753507,0.00005125245,0.00003133221,0.00005253275],"domain_scores_gemma":[0.9997824,0.0000913495,0.00004012555,0.00001142667,0.00002711289,0.00004759654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002223002,0.00002299421,0.0001811136,0.00002130709,0.000006342922,0.00001472708,0.00001442502,0.00008814994,0.998625,0.00005674587,0.00003701236,0.0007099981],"study_design_scores_gemma":[0.00002345422,0.0001394124,0.007294596,0.000006154706,0.000009882428,0.00009611947,0.00001732294,0.003717344,0.9877235,0.00005916116,0.0009042257,0.000008778639],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970725,0.0007636016,0.001350314,0.00003687208,0.000009533753,0.00001154876,0.0001078907,0.00001990986,0.000627926],"genre_scores_gemma":[0.9978111,0.0001648214,0.0009645408,0.00003621042,0.000003651397,0.00001145841,0.0001773587,0.00001251788,0.0008182818],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002851923,"threshold_uncertainty_score":0.008736312,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02664269746013085,"score_gpt":0.2689068344234853,"score_spread":0.2422641369633544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}