{"id":"W2522026215","doi":"10.1016/j.bbamcr.2016.09.015","title":"Inhibition of autophagy sensitises cells to hydrogen peroxide-induced apoptosis: Protective effect of mild thermotolerance acquired at 40 °C","year":2016,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Autophagy; Apoptosis; Cell biology; Programmed cell death; Oxidative stress; Reactive oxygen species; Unfolded protein response; Endoplasmic reticulum; Bafilomycin; Chemistry; HeLa; Biology; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002141343,0.0005507641,0.0005792398,0.0002127528,0.000308501,0.0002297213,0.0002389132,0.0004317109,0.003508905],"category_scores_gemma":[0.0001451408,0.0002350123,0.000584887,0.0002517677,0.0004143321,0.0003303145,0.0002815779,0.00108212,0.0003719747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002162214,"about_ca_system_score_gemma":0.0003811398,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006779785,"about_ca_topic_score_gemma":0.000906732,"domain_scores_codex":[0.9998664,0.00002630038,0.00001912603,0.00002128741,0.00002043628,0.00004661936],"domain_scores_gemma":[0.999904,0.00001546906,0.00001748057,0.00002038068,0.00001146231,0.00003119168],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001423932,0.0001091428,0.0001377495,0.00007551815,0.00002169758,0.0000811557,0.00003545721,0.00008814705,0.9965754,0.0001463942,0.0001381606,0.00116719],"study_design_scores_gemma":[0.00007963948,0.0009602765,0.001844097,0.000009044131,0.0000317056,0.0001412374,0.00003477984,0.0002870171,0.9951929,0.00008077383,0.001329813,0.000008931426],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945755,0.001353441,0.001924633,0.0002635638,0.000134396,0.00005612623,0.0004045539,0.0001357809,0.001151996],"genre_scores_gemma":[0.9957097,0.0009136264,0.001232782,0.00008552412,0.00002801065,0.00007255915,0.0005187051,0.0000195529,0.001419508],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003508905,"threshold_uncertainty_score":0.01173842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02379228786986489,"score_gpt":0.3198272234736492,"score_spread":0.2960349356037844,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}