{"id":"W2522328851","doi":"10.3892/or.2016.5119","title":"RUNX1 truncation resulting from a cryptic and novel t(6;21)(q25;q22) chromosome translocation in acute myeloid leukemia: A case report","year":2016,"lang":"en","type":"article","venue":"Oncology Reports","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Biology; Fusion transcript; RUNX1; Chromosomal translocation; Fluorescence in situ hybridization; Myeloid leukemia; Molecular biology; NPM1; Genetics; Sanger sequencing; Breakpoint; Trisomy; Karyotype; DNA sequencing; Cancer research; Chromosome; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00183991,0.0003134988,0.000794357,0.000394807,0.000142795,0.00002496799,0.0000874238,0.000607324,0.0001088988],"category_scores_gemma":[0.001705567,0.0002408321,0.00009909245,0.0004612739,0.0003123235,0.0003201784,0.00009885058,0.000594141,0.00002963804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003316267,"about_ca_system_score_gemma":0.002831318,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002071516,"about_ca_topic_score_gemma":0.0007942807,"domain_scores_codex":[0.9962689,0.0001405943,0.00144949,0.001085368,0.0004430686,0.0006125665],"domain_scores_gemma":[0.9972094,0.0005413224,0.0006800951,0.0009292613,0.0002998762,0.000340075],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0004339955,0.0002148082,0.02155039,0.00004379716,0.0001816206,0.4734235,0.001121132,0.000003095276,0.463371,0.00003575564,0.0007146547,0.03890625],"study_design_scores_gemma":[0.009949866,0.0008134553,0.09145564,0.0005723137,0.0004197987,0.8633701,0.000458508,0.0007321209,0.02196834,0.0007037944,0.009102336,0.0004537917],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878931,0.0002826316,0.001762365,0.006478691,0.0003024559,0.001107595,0.00001811518,0.0001266902,0.002028362],"genre_scores_gemma":[0.9898569,0.0002698433,0.006418266,0.0003137851,0.0003656478,0.0002659218,0.0001498633,0.00006186841,0.00229792],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4414026,"threshold_uncertainty_score":0.982085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02440889093231503,"score_gpt":0.3220361762967477,"score_spread":0.2976272853644327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}