{"id":"W2522762427","doi":"10.2337/dci16-0025","title":"Response to Comment on Rickels et al. Intranasal Glucagon for Treatment of Insulin-Induced Hypoglycemia in Adults With Type 1 Diabetes: A Randomized Crossover Noninferiority Study. Diabetes Care 2016;39:264–270","year":2016,"lang":"en","type":"letter","venue":"Diabetes Care","topic":"Diabetes Management and Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"GDI Integrated Facility Services (Canada)","funders":"National Center for Advancing Translational Sciences; National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Medicine; Hypoglycemia; Nasal administration; Crossover study; Glucagon; Type 2 diabetes; Diabetes mellitus; Insulin; Randomized controlled trial; Intensive care medicine; Internal medicine; Endocrinology; Pharmacology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004021888,0.0009158367,0.001954005,0.0007298034,0.001821596,0.001839757,0.002733034,0.03427554,0.007482642],"category_scores_gemma":[0.02397487,0.0006455292,0.001465198,0.0008368124,0.001794609,0.002178276,0.0008374362,0.02672564,0.0101016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004101057,"about_ca_system_score_gemma":0.002210345,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005421572,"about_ca_topic_score_gemma":0.005674588,"domain_scores_codex":[0.9972583,0.0008141379,0.0004808132,0.0003603887,0.0008006987,0.0002856671],"domain_scores_gemma":[0.993676,0.0030348,0.0006900181,0.0002528929,0.001579013,0.0007672248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001937201,0.00004402864,0.00052087,0.00008259733,0.00001986416,0.000863924,0.00006487345,0.0000323503,0.0001278956,0.0005113214,0.9927556,0.004783094],"study_design_scores_gemma":[0.0007308139,0.0004506976,0.004567051,0.0007402254,0.0001280212,0.003838811,0.0005870615,0.0008414609,0.000952475,0.004217083,0.9827901,0.0001562589],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0005809631,0.000952371,0.00008684562,0.9709791,0.02584223,0.00003745603,0.0001649216,0.0000921823,0.001264024],"genre_scores_gemma":[0.004130242,0.000678623,0.0001943702,0.9546926,0.03587468,0.0000870198,0.00005645468,0.00003137643,0.00425465],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03427554,"threshold_uncertainty_score":0.02975535,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01753734383899194,"score_gpt":0.3041024423073793,"score_spread":0.2865650984683873,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}