{"id":"W2523230898","doi":"10.1182/blood.v104.11.3895.3895","title":"Leptin-Mediated Activation of Human Platelets: Involvement of a Leptin Receptor and Phosphodiesterase 3A Cellular Signaling Complex.","year":2004,"lang":"en","type":"article","venue":"Blood","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Leptin; Internal medicine; Phosphorylation; Platelet activation; Phosphodiesterase; Endocrinology; Leptin receptor; Wortmannin; Protein kinase B; Chemistry; Platelet; Cell biology; Biology; Biochemistry; Medicine; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003127518,0.0004805477,0.0001856466,0.000337143,0.0002365935,0.0004353904,0.0001865323,0.0004022192,0.001969747],"category_scores_gemma":[0.0002291236,0.0002392184,0.0003798474,0.0002001436,0.0002001955,0.0002273206,0.0002515787,0.0005468433,0.0004512267],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004111923,"about_ca_system_score_gemma":0.0002018712,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007804876,"about_ca_topic_score_gemma":0.0007423908,"domain_scores_codex":[0.9997255,0.0001103884,0.00001623251,0.00003016355,0.00006624868,0.00005146498],"domain_scores_gemma":[0.9999365,0.00002012797,0.0000166636,0.000006579106,0.000006937803,0.00001319908],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005365107,0.00005778447,0.0002531124,0.0001487415,0.00002518312,0.0006443224,0.00004820413,0.00008429976,0.9942579,0.000637018,0.0001793744,0.003127512],"study_design_scores_gemma":[0.0003657755,0.0009739913,0.02937483,0.0000511475,0.00007930512,0.002945342,0.0001039062,0.003955901,0.9513114,0.000803544,0.010018,0.00001687393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9496153,0.02800202,0.01257802,0.001325328,0.0002231407,0.0003217688,0.0007815088,0.00010744,0.007045542],"genre_scores_gemma":[0.9873369,0.004971174,0.004463956,0.0002525148,0.0000585943,0.0001773251,0.0005795506,0.000009499848,0.002150352],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001969747,"threshold_uncertainty_score":0.006589472,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03070316590960195,"score_gpt":0.2581517608026543,"score_spread":0.2274485948930524,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}