{"id":"W2523400423","doi":"10.1371/journal.pgen.1006336","title":"Experimental Evolution of Gene Expression and Plasticity in Alternative Selective Regimes","year":2016,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Evolution and Genetic Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":110,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Phenotypic plasticity; Plasticity; Evolutionary biology; Adaptation (eye); Genetics; Gene expression; Drosophila melanogaster; Transcriptome; Population; Allele; Gene; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003906207,0.0001119216,0.0001148688,0.0000546292,0.00002535317,0.000003603811,0.00008801414,0.00009875068,0.000007221252],"category_scores_gemma":[0.00005654488,0.00008960709,0.00002656646,0.00005541435,0.0001233715,0.000003023182,0.00008702528,0.00003477265,0.000001778879],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004419677,"about_ca_system_score_gemma":0.00004640554,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005122314,"about_ca_topic_score_gemma":0.00001709165,"domain_scores_codex":[0.9992311,0.00005543783,0.0001766037,0.0002653065,0.0001192898,0.0001522519],"domain_scores_gemma":[0.9996412,0.00001736198,0.00008120326,0.0001327857,0.00007336491,0.00005410333],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008533223,0.0001159471,0.01578869,0.00000628836,0.00001692446,5.712629e-7,0.0001039909,0.0001704464,0.9834474,0.00008662054,0.00006218503,0.0001156102],"study_design_scores_gemma":[0.0007889291,0.0003234264,0.00724097,0.00003344067,0.00000711319,0.00000448397,0.00009748249,0.001613915,0.9895102,0.0001973609,0.00006144586,0.0001212185],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874018,0.001247109,0.01079046,0.00002172989,0.00004169302,0.0001384203,0.00002685526,0.000005211765,0.0003266679],"genre_scores_gemma":[0.9970882,0.0001522663,0.002504188,0.00001425279,0.00006206882,0.00001365832,0.000006848241,0.00001329193,0.0001452557],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009686318,"threshold_uncertainty_score":0.3654071,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008485522832391882,"score_gpt":0.241213534333126,"score_spread":0.2327280115007341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}