{"id":"W2523490165","doi":"10.1200/jco.2013.31.15_suppl.8510","title":"MM-003: A phase III, multicenter, randomized, open-label study of pomalidomide (POM) plus low-dose dexamethasone (LoDEX) versus high-dose dexamethasone (HiDEX) in relapsed/refractory multiple myeloma (RRMM).","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital","funders":"","keywords":"Medicine; Pomalidomide; Lenalidomide; Thalidomide; Clinical endpoint; Neutropenia; Internal medicine; Dexamethasone; Phases of clinical research; Surgery; Population; Multiple myeloma; Gastroenterology; Randomized controlled trial; Toxicity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00252414,0.002250271,0.002395877,0.0005352321,0.0004929841,0.00146344,0.001610871,0.001723812,0.006281402],"category_scores_gemma":[0.001379563,0.0009528793,0.001662808,0.0006497245,0.001318119,0.001136888,0.0005918462,0.003930649,0.001401653],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001280223,"about_ca_system_score_gemma":0.002202543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001470158,"about_ca_topic_score_gemma":0.003858656,"domain_scores_codex":[0.999438,0.0003164011,0.00002724157,0.00008313444,0.00004159857,0.0000936483],"domain_scores_gemma":[0.9990174,0.0001879101,0.000207361,0.00005341889,0.00003776086,0.0004962239],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9429181,0.02675193,0.001186357,0.0004633481,0.0006929106,0.00005396221,0.00009991371,0.0007052034,0.006883787,0.0001900526,0.001412585,0.01864193],"study_design_scores_gemma":[0.8782424,0.1173938,0.001949708,0.00002227601,0.0002720178,0.00005041719,0.00002837886,0.0005601791,0.0005689566,0.0001406481,0.0007552403,0.00001589878],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856358,0.002739455,0.0007746646,0.0007348943,0.0003552946,0.005704098,0.001798262,0.0002438476,0.00201362],"genre_scores_gemma":[0.9785423,0.002484497,0.003209364,0.001972616,0.0003685015,0.007389574,0.002238994,0.0000670023,0.00372716],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006281402,"threshold_uncertainty_score":0.02101338,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1816847371527139,"score_gpt":0.4888007598015487,"score_spread":0.3071160226488348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}