{"id":"W2524077981","doi":"10.21769/bioprotoc.1659","title":"In vitro and in vivo Limiting Dilution Assay for Colorectal Cancer","year":2015,"lang":"en","type":"article","venue":"BIO-PROTOCOL","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Colorectal cancer; In vivo; In vitro; Cell culture; Cancer; Population; Cancer cell; Cell; Cancer research; Chemistry; Biology; Oncology; Molecular biology; Medicine; Internal medicine; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0028094,0.002162452,0.001195756,0.003018474,0.0008169256,0.0008634384,0.001171494,0.001250651,0.01725872],"category_scores_gemma":[0.001813212,0.000773312,0.0009302287,0.002145091,0.0007236321,0.0007639836,0.0007539256,0.00350846,0.01152291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005419321,"about_ca_system_score_gemma":0.0006372438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007730302,"about_ca_topic_score_gemma":0.002175641,"domain_scores_codex":[0.9948798,0.002185288,0.000512652,0.0006915802,0.001417028,0.0003135334],"domain_scores_gemma":[0.9966992,0.001053945,0.0003394606,0.0008134359,0.0008773749,0.0002166688],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002321226,0.000440538,0.0008980117,0.0003351956,0.00003632549,0.0001577323,0.0001861933,0.0001602901,0.9846271,0.001181076,0.002416068,0.009329402],"study_design_scores_gemma":[0.00004331196,0.001026719,0.004387778,0.00006964189,0.0001035275,0.001124215,0.00008393032,0.002121878,0.9470206,0.0004728387,0.04349156,0.00005397869],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.1566791,0.01515426,0.7136174,0.001205957,0.00135042,0.006516934,0.01202686,0.008901181,0.08454787],"genre_scores_gemma":[0.2580208,0.01487233,0.5378739,0.0009398957,0.0004828139,0.01097301,0.02809469,0.00125692,0.1474856],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.01725872,"threshold_uncertainty_score":0.05773622,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05206732218161741,"score_gpt":0.3636827840030575,"score_spread":0.3116154618214401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}