{"id":"W2524077981","doi":"10.21769/bioprotoc.1659","title":"In vitro and in vivo Limiting Dilution Assay for Colorectal Cancer","year":2015,"lang":"en","type":"article","venue":"BIO-PROTOCOL","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Colorectal cancer; In vivo; In vitro; Cell culture; Cancer; Population; Cancer cell; Cell; Cancer research; Chemistry; Biology; Oncology; Molecular biology; Medicine; Internal medicine; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004276499,0.00009601945,0.0002085802,0.00009740159,0.00001874304,0.00001236966,0.00002904035,0.00006882905,0.00004951854],"category_scores_gemma":[0.0001097094,0.00008166811,0.00003318745,0.0001514338,0.00003182122,0.00006625869,0.00002500927,0.00008378387,0.000001833288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002442447,"about_ca_system_score_gemma":0.0001886459,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007701408,"about_ca_topic_score_gemma":0.000824194,"domain_scores_codex":[0.9992408,0.00003082942,0.0002017558,0.0001984908,0.0001178346,0.0002102588],"domain_scores_gemma":[0.9996697,0.00003813717,0.00005952892,0.00007407253,0.00005293349,0.0001056137],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01590031,0.0004534244,0.04868016,0.001039081,0.00003382685,0.00004876746,0.0008215492,0.00001496568,0.835834,0.00007702961,0.01407491,0.08302192],"study_design_scores_gemma":[0.01449858,0.0004010321,0.005306531,0.0002000266,0.00002191593,0.0000117292,0.0001981911,0.0008086861,0.5857013,0.00008372918,0.3925934,0.0001748128],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.1603633,0.00003388788,0.0001125969,0.001121533,0.0001474572,0.8359665,0.00005515354,0.00003106939,0.00216852],"genre_scores_gemma":[0.1244165,0.000001290673,0.0009669499,0.0002169966,0.0002235943,0.8739405,0.000002788359,0.00001404771,0.0002173603],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.3785185,"threshold_uncertainty_score":0.3330329,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05206732218161741,"score_gpt":0.3636827840030575,"score_spread":0.3116154618214401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}