{"id":"W2524199030","doi":"10.1016/j.jasc.2016.07.150","title":"Distinguishing Pre-analytical From Analytical Error in Immunohistochemistry (IHC) for Estrogen Receptor (ER), Progesterone Receptor (PR), and Mammoglobin: A Multi-laboratory Pilot Study Using American Type Culture Collection Cell Lines","year":2016,"lang":"en","type":"article","venue":"Journal of the American Society of Cytopathology","topic":"Molecular Biology Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; Calgary Laboratory Services","funders":"","keywords":"Progesterone receptor; Medicine; Immunohistochemistry; Estrogen receptor; Estrogen; Receptor; Cell culture; Internal medicine; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004093359,0.0001917468,0.0005055395,0.00002955072,0.00009639353,0.00001149159,0.0003215541,0.00009940359,0.000002559015],"category_scores_gemma":[0.0002693246,0.0001282444,0.0001921895,0.0002779774,0.0008295288,0.000007319907,0.0001596714,0.0002084348,1.891797e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009574676,"about_ca_system_score_gemma":0.0001735759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008013307,"about_ca_topic_score_gemma":0.000007104166,"domain_scores_codex":[0.998579,0.0002124351,0.0005349718,0.0003295997,0.0001203371,0.0002236356],"domain_scores_gemma":[0.9982252,0.00005494109,0.0009839325,0.0003202075,0.0003396235,0.00007614971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005734114,0.0004466942,0.05925202,0.00001093065,0.00009937679,0.000001077689,0.0001602106,0.000004947618,0.9379362,0.000002032979,0.001137822,0.0003753031],"study_design_scores_gemma":[0.007847726,0.02659426,0.09368412,0.0002937417,0.001106,0.0002388721,0.006694351,0.001876762,0.852369,0.00009616972,0.007952664,0.001246331],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918044,0.0003233236,0.006766764,0.0005530124,0.00005911105,0.000392064,0.0000917693,0.000006443055,0.000003155128],"genre_scores_gemma":[0.9381382,0.0001741058,0.06120877,0.0001840635,0.0001435972,0.00002536933,0.00001181776,0.00002414235,0.00008988904],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08556717,"threshold_uncertainty_score":0.5229654,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02589934806928158,"score_gpt":0.3309707988576336,"score_spread":0.305071450788352,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}