{"id":"W2524244294","doi":"10.1186/s12858-016-0074-9","title":"Identification of replication-dependent and replication-independent linker histone complexes: Tpr specifically promotes replication-dependent linker histone stability","year":2016,"lang":"en","type":"article","venue":"BMC Biochemistry","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Cancer Institute; Hakai Institute; National Institutes of Health","keywords":"Histone H1; Biology; Histone H2A; Histone code; Histone; Linker; Cell biology; Histone methyltransferase; Histone methylation; Origin recognition complex; Replication factor C; DNA replication; Genetics; Control of chromosome duplication; Eukaryotic DNA replication; DNA; Nucleosome; Gene; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002923794,0.0003704408,0.0002697812,0.0002294951,0.0001949875,0.0004155072,0.0003434129,0.0003261763,0.001694624],"category_scores_gemma":[0.0002431702,0.0001833377,0.0004247182,0.0001690288,0.0002573446,0.0001837653,0.0003259988,0.0005863481,0.0006587332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005139717,"about_ca_system_score_gemma":0.0002146993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003850036,"about_ca_topic_score_gemma":0.0007939753,"domain_scores_codex":[0.9997581,0.00002343532,0.00001775402,0.00008114637,0.00006624666,0.00005336615],"domain_scores_gemma":[0.9997613,0.00004934218,0.00007340522,0.00002715859,0.00002848001,0.00006036226],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004072036,0.000009672624,0.0001141541,0.00001891737,0.000004170914,0.00001831382,0.000004243632,0.00001620212,0.9994313,0.00002242769,0.00002048615,0.0002992736],"study_design_scores_gemma":[0.00001141804,0.00008948135,0.00450656,0.000003810241,0.00001205907,0.0002470897,0.00001211405,0.0007955225,0.9932778,0.00001891012,0.001021676,0.00000356715],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869922,0.002183804,0.008630881,0.0001671206,0.00003020171,0.0000589116,0.0005734107,0.0001528441,0.00121047],"genre_scores_gemma":[0.9891781,0.0005915002,0.006679228,0.0000862485,0.00001248231,0.00002729149,0.001382857,0.0000684736,0.001973785],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001694624,"threshold_uncertainty_score":0.005669057,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01815485385352045,"score_gpt":0.2736122345912185,"score_spread":0.255457380737698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}