{"id":"W2524406518","doi":"10.1002/slct.201600789","title":"Antimicrobial and Antitumor Screening of Fluorescent 5,7‐Dihydroxy‐4‐Propyl‐ <i>2H</i> ‐Chromen‐2‐One Derivatives with Docking Studies","year":2016,"lang":"en","type":"article","venue":"ChemistrySelect","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Prince Edward Island","funders":"Natural Sciences and Engineering Research Council of Canada; Ministry of Education, India; Taibah University; Ministry of Earth Sciences","keywords":"Antimicrobial; DNA gyrase; Novobiocin; Docking (animal); Chemistry; Stereochemistry; Fluorescence; Combinatorial chemistry; Potency; Biochemistry; Antibiotics; In vitro; Escherichia coli; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001323166,0.0003786503,0.0002755488,0.0003551529,0.0001212885,0.0001379458,0.0002565936,0.0002347029,0.001088171],"category_scores_gemma":[0.00008555959,0.0001376153,0.0002117169,0.0002214706,0.0001470837,0.0001304155,0.0001192007,0.0002207661,0.0002156502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002367217,"about_ca_system_score_gemma":0.0001963153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001069222,"about_ca_topic_score_gemma":0.001858399,"domain_scores_codex":[0.9999352,0.00001653761,0.000002891256,0.00001045867,0.0000172625,0.0000176721],"domain_scores_gemma":[0.9999572,0.000006843143,0.000007345242,0.000003676404,0.000008575509,0.00001625994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003067373,0.0003126661,0.0005412534,0.00018826,0.00001787918,0.0001606633,0.00002411307,0.002343099,0.9881129,0.0002230355,0.0001738772,0.007595493],"study_design_scores_gemma":[0.000159119,0.003780279,0.00606647,0.0000217629,0.00005499185,0.0003928771,0.00002711973,0.006059578,0.9793603,0.00007505799,0.003977733,0.00002462603],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985307,0.006701185,0.002984655,0.0001444391,0.00003091913,0.00009791824,0.0004716401,0.0001079217,0.004154367],"genre_scores_gemma":[0.9918299,0.002698918,0.003019876,0.00004711444,0.000007229942,0.00003389383,0.0005599466,0.000007951731,0.001795172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001088171,"threshold_uncertainty_score":0.003640294,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0350033524585471,"score_gpt":0.2461488280884083,"score_spread":0.2111454756298612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}