{"id":"W2524406518","doi":"10.1002/slct.201600789","title":"Antimicrobial and Antitumor Screening of Fluorescent 5,7‐Dihydroxy‐4‐Propyl‐ <i>2H</i> ‐Chromen‐2‐One Derivatives with Docking Studies","year":2016,"lang":"en","type":"article","venue":"ChemistrySelect","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Prince Edward Island","funders":"Natural Sciences and Engineering Research Council of Canada; Ministry of Education, India; Taibah University; Ministry of Earth Sciences","keywords":"Antimicrobial; DNA gyrase; Novobiocin; Docking (animal); Chemistry; Stereochemistry; Fluorescence; Combinatorial chemistry; Potency; Biochemistry; Antibiotics; In vitro; Escherichia coli; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001313705,0.0002669387,0.0004969288,0.00001953601,0.0001203051,0.00002236454,0.000177353,0.0001073635,0.0001597355],"category_scores_gemma":[0.0002824585,0.0001512792,0.00006670094,0.0001220697,0.0004950251,0.00009379373,0.0001450044,0.0001236875,0.000001368213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004543392,"about_ca_system_score_gemma":0.00003155957,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007321376,"about_ca_topic_score_gemma":0.000001647292,"domain_scores_codex":[0.9986917,0.00001819879,0.000269916,0.0004788254,0.0001819673,0.000359401],"domain_scores_gemma":[0.9990492,0.0002843913,0.0002268903,0.0002363834,0.0001228306,0.00008030001],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001505548,0.0001285191,0.02047847,0.0003840001,0.0001947817,0.000008188565,0.0000571589,4.725227e-7,0.9682212,0.00000479764,0.00008571737,0.01028607],"study_design_scores_gemma":[0.00070053,0.00004575222,0.001730155,0.000901583,0.00004370673,0.00003535305,0.00009186719,0.000005488078,0.9959561,0.00002606318,0.0001849758,0.000278375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979138,0.0005781773,0.0001498236,0.0002602362,0.000009760213,0.00005768501,0.00003052109,0.00006912283,0.0009308826],"genre_scores_gemma":[0.9978814,0.0004163238,0.001379315,0.00002436657,0.0001306571,0.00001228631,0.000004752934,0.00001980247,0.0001311005],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02773488,"threshold_uncertainty_score":0.6168988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0350033524585471,"score_gpt":0.2461488280884083,"score_spread":0.2111454756298612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}