{"id":"W2524677712","doi":"10.1016/j.cjca.2016.07.345","title":"YOUNG BONE MARROW SCA-1 CELLS REJUVENATE AGED HEART TO ENHANCE CARDIAC REPAIR BY PROMOTING EPITHELIAL-TO-MESENCHYMAL TRANSITION THROUGH TGF-β SIGNALING","year":2016,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Public Health","funders":"","keywords":"Medicine; Mesenchymal stem cell; Bone marrow; Progenitor cell; Stem cell; Heart failure; Cell biology; Population; Epithelial–mesenchymal transition; Cancer research; Pathology; Immunology; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002284925,0.000312053,0.0004587192,0.000306286,0.0001671273,0.0003537943,0.0001889797,0.0003404075,0.001765264],"category_scores_gemma":[0.00008161998,0.0001709896,0.0003855599,0.000131093,0.000193347,0.000320026,0.0002202211,0.001498727,0.0005853672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001136903,"about_ca_system_score_gemma":0.0002462742,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006850382,"about_ca_topic_score_gemma":0.002349512,"domain_scores_codex":[0.9998891,0.000008951701,0.00001164476,0.00002194781,0.00003481221,0.00003349617],"domain_scores_gemma":[0.9998794,0.000009277682,0.00003289315,0.000009088903,0.00001455657,0.00005479832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00017199,0.0001066379,0.0003567341,0.00006377861,0.00001552319,0.00009827616,0.00005035824,0.00006771519,0.9953367,0.0001122475,0.0001846171,0.003435326],"study_design_scores_gemma":[0.0001845402,0.001491072,0.01635391,0.00005055274,0.0001721901,0.0005553978,0.0002615232,0.001322748,0.9665572,0.0002105298,0.01282477,0.00001556017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897794,0.003641583,0.003743487,0.0002297288,0.0002010336,0.00006609568,0.0004352417,0.0001298271,0.001773471],"genre_scores_gemma":[0.9888855,0.002244219,0.002456821,0.0001855469,0.0000684527,0.00006099368,0.0004917654,0.00004721765,0.005559473],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001765264,"threshold_uncertainty_score":0.00590533,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00813777235695279,"score_gpt":0.2405312373000066,"score_spread":0.2323934649430538,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}