{"id":"W2524772133","doi":"10.1016/j.cjca.2016.07.480","title":"GLYOXYLASE 1 OVER EXPRESSION ATTENUATES THE ADVERSE EFFECTS OF CHRONIC HYPERGLYCEMIA ON THE THERAPEUTIC REGENERATION BY EXPLANT DERIVED CARDIAC STEM CELLS","year":2016,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Methylglyoxal; Medicine; Diabetes mellitus; Myocardial infarction; Stem cell; Ex vivo; Regeneration (biology); Explant culture; Internal medicine; Detoxification (alternative medicine); In vivo; Cardiology; Pharmacology; Endocrinology; In vitro; Enzyme; Cell biology; Pathology; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001788434,0.000428286,0.0003267113,0.0002551808,0.0001626691,0.000414098,0.000217922,0.000293828,0.0022334],"category_scores_gemma":[0.00008647152,0.0001462256,0.0002975755,0.000161214,0.0003488066,0.0002182643,0.0001668167,0.001441987,0.0003929282],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002001485,"about_ca_system_score_gemma":0.0004165106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006038598,"about_ca_topic_score_gemma":0.0009491036,"domain_scores_codex":[0.9998626,0.00001274597,0.00001509847,0.00003142323,0.00003267004,0.00004545771],"domain_scores_gemma":[0.9998547,0.00001830167,0.00004395403,0.00001430259,0.00001033785,0.00005831632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003924815,0.0001180346,0.0001527755,0.00002958762,0.00000751106,0.00005067981,0.00002132175,0.00005669697,0.9972899,0.0001003702,0.00008007748,0.001700701],"study_design_scores_gemma":[0.00003954251,0.0007051823,0.002564389,0.000008342843,0.00004379858,0.0001117339,0.00006769744,0.0004606675,0.9942647,0.00005157812,0.00167714,0.000005115124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996098,0.000796302,0.001405413,0.0001492513,0.0001126572,0.00002284179,0.0002722828,0.00007764486,0.0010655],"genre_scores_gemma":[0.9940363,0.0008249172,0.0009773729,0.00007812703,0.00002299892,0.00003477131,0.0004570164,0.00002774003,0.003540735],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0022334,"threshold_uncertainty_score":0.007471442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01004071235211301,"score_gpt":0.2318975384817228,"score_spread":0.2218568261296098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}