{"id":"W2524917460","doi":"10.1016/j.cell.2016.08.032","title":"Loss of the HVEM Tumor Suppressor in Lymphoma and Restoration by Modified CAR-T Cells","year":2016,"lang":"en","type":"article","venue":"Cell","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":243,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Center for Research Resources; National Cancer Institute","keywords":"Biology; Suppressor; Lymphoma; Cancer research; Cell biology; Immunology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003561715,0.0004299843,0.0003958245,0.0005411634,0.0002720596,0.0006493825,0.0005660213,0.0007288925,0.002349931],"category_scores_gemma":[0.000265458,0.0002808363,0.0003574626,0.00022739,0.0007835735,0.0005104888,0.000352728,0.001601503,0.0004747633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003612107,"about_ca_system_score_gemma":0.0002743278,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006349071,"about_ca_topic_score_gemma":0.0005333908,"domain_scores_codex":[0.9995053,0.000109744,0.00004256181,0.0000758833,0.00008426893,0.0001822783],"domain_scores_gemma":[0.9997892,0.00006128057,0.00004840079,0.00003828146,0.00001117037,0.00005169237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006010656,0.0001880833,0.0002457729,0.00003439084,0.00001176252,0.0001640803,0.00004928037,0.0002998634,0.9950829,0.001076434,0.00009316733,0.00215326],"study_design_scores_gemma":[0.00008514505,0.0006335051,0.001118534,0.000003250124,0.00002294233,0.000506782,0.00004521856,0.001651571,0.9935896,0.000154257,0.002183112,0.000005919398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956434,0.0006571912,0.001899224,0.00009570716,0.00004424895,0.00002764282,0.0001755812,0.0001701258,0.0012868],"genre_scores_gemma":[0.9975628,0.0001076806,0.0005700124,0.00001879774,0.00000983068,0.00001965164,0.0001441109,0.00002975067,0.001537427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002349931,"threshold_uncertainty_score":0.007861316,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0182748629749977,"score_gpt":0.2650378276755643,"score_spread":0.2467629647005666,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}