{"id":"W2525272420","doi":"10.1177/2326409816666296","title":"Integrated Multianalyte Second-Tier Testing for Newborn Screening for MSUD, IVA, and GAMT Deficiencies","year":2016,"lang":"en","type":"article","venue":"Journal of Inborn Errors of Metabolism and Screening","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; BC Children's Hospital; University of British Columbia","funders":"","keywords":"Maple syrup urine disease; Screening test; Newborn screening; Chromatography; Chemistry; Computer science; Medicine; Pediatrics; Biochemistry; Amino acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00224282,0.001003328,0.0008266195,0.002185138,0.0004552449,0.001108276,0.0007802931,0.0007708722,0.001326622],"category_scores_gemma":[0.00235281,0.000657216,0.0006102119,0.000585413,0.0003491459,0.0003576622,0.001010662,0.001150682,0.0005235333],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004797431,"about_ca_system_score_gemma":0.0007831574,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003360136,"about_ca_topic_score_gemma":0.01079398,"domain_scores_codex":[0.9973334,0.0006710747,0.0001692186,0.0004714822,0.001161078,0.0001937541],"domain_scores_gemma":[0.9982856,0.0004847371,0.0002362965,0.0002676536,0.0004415117,0.0002841869],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001866527,0.001097925,0.1420791,0.0002162895,0.000403305,0.0006491559,0.0003562944,0.00129143,0.7689655,0.0003666409,0.002005852,0.08070198],"study_design_scores_gemma":[0.0001269997,0.003063108,0.2484035,0.00009070174,0.0004480277,0.005133265,0.0001425259,0.02085644,0.7143447,0.0003237982,0.00694102,0.0001260035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8709669,0.003469727,0.1120165,0.0007325904,0.0002934395,0.0009771491,0.001792661,0.005186681,0.004564423],"genre_scores_gemma":[0.8779659,0.0005190499,0.1158662,0.0005757326,0.00006891797,0.0002712953,0.001580017,0.0002193697,0.002933512],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003360136,"threshold_uncertainty_score":0.01186132,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0317321126622369,"score_gpt":0.2677931221017646,"score_spread":0.2360610094395277,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}