{"id":"W2525315844","doi":"10.1080/15384101.2016.1237769","title":"Checkpoint adaptation: Keeping Cdc5 in the T-loop","year":2016,"lang":"en","type":"letter","venue":"Cell Cycle","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Biology; CHEK1; G2-M DNA damage checkpoint; Cell biology; DNA damage; Genetics; Chromosome; Adaptation (eye); Kinase; DNA; Cell cycle; Gene; Cell cycle checkpoint; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002601235,0.0001948097,0.0001409032,0.00003892789,0.00005506368,0.00002922529,0.0004273643,0.0004985256,0.000072613],"category_scores_gemma":[0.0000294145,0.0001387697,0.0001297623,0.00005694986,0.00006458454,0.000002391638,0.0001010871,0.0003641971,0.0001469501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002698654,"about_ca_system_score_gemma":0.00005976373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002454216,"about_ca_topic_score_gemma":0.00002186032,"domain_scores_codex":[0.9987745,0.0001272187,0.0002020571,0.0003943068,0.0001716486,0.0003302512],"domain_scores_gemma":[0.9992088,0.00002232963,0.0001005079,0.000609382,0.00003656181,0.00002241679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001884836,0.00003623638,0.00001982365,0.0001541879,0.0000315773,0.00019519,0.0003794024,0.00002381284,0.3114244,0.00001982571,0.6817898,0.00590693],"study_design_scores_gemma":[0.0003072007,0.00008291858,0.00002572214,0.00004919072,0.00001443096,0.00001769071,0.00008397588,0.00003132442,0.129235,0.000699887,0.8691978,0.0002548086],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.2273883,0.005912066,0.009326166,0.5002512,0.002693872,0.002284073,0.0001375029,0.0001509634,0.2518558],"genre_scores_gemma":[0.1229914,0.0004195659,0.001871928,0.8260309,0.01025322,0.0002564065,0.0008021934,0.0001933371,0.03718112],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.3257796,"threshold_uncertainty_score":0.5658863,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01336114523955853,"score_gpt":0.2225527102725017,"score_spread":0.2091915650329431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}