{"id":"W2525564587","doi":"10.1158/1078-0432.ccr-16-0844","title":"Patient-Derived Xenograft Establishment from Human Malignant Pleural Mesothelioma","year":2016,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Occupational and environmental lung diseases","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen Elizabeth II Health Sciences Centre; University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Medicine; Pemetrexed; Mesothelioma; Cisplatin; Cancer; Pathology; Oncology; Chemotherapy; Pleural disease; Cancer research; Internal medicine; Respiratory disease; Lung","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005935101,0.0002677714,0.0002611505,0.0003314211,0.0001980303,0.0003049902,0.0001912935,0.0002910313,0.001728498],"category_scores_gemma":[0.0006319194,0.0001639316,0.0003224387,0.0003220635,0.0001814212,0.0002695182,0.0003635694,0.0004596784,0.0004867472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001992692,"about_ca_system_score_gemma":0.0001965159,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00042515,"about_ca_topic_score_gemma":0.000424585,"domain_scores_codex":[0.9997075,0.00006924955,0.00004237955,0.00005407271,0.00009770502,0.00002901506],"domain_scores_gemma":[0.9995153,0.0001595101,0.00006347847,0.0001418169,0.00006368282,0.00005626601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001426838,0.0004562285,0.06337366,0.000233612,0.0001010575,0.0006987901,0.0002028733,0.001149471,0.9210965,0.0002749096,0.0004655912,0.01052061],"study_design_scores_gemma":[0.0001779803,0.01064245,0.2588423,0.00004465942,0.0002118834,0.01348499,0.0003708363,0.00796642,0.6983469,0.0002172239,0.009668601,0.00002577983],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962566,0.0005376215,0.001944766,0.00001705652,0.00001327006,0.00006658026,0.0005795237,0.00003092345,0.0005536574],"genre_scores_gemma":[0.9952424,0.0003455521,0.001909907,0.00001615792,0.000004898529,0.00004818748,0.002061774,0.000008572568,0.0003626439],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001728498,"threshold_uncertainty_score":0.005782425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1827863891041366,"score_gpt":0.4907957922405757,"score_spread":0.3080094031364391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}