{"id":"W2525727773","doi":"10.1093/rheumatology/keu101.024","title":"103. Long-Term Safety and Efficacy of Certolizumab Pegol in Combination with Methotrexate in the Treatment of Rheumatoid Arthritis: 5-Year Results from a 52-Week Randomized Controlled Trial and Open-Label Extension Study","year":2014,"lang":"en","type":"article","venue":"Lara D. Veeken","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Medicine; Certolizumab pegol; Rheumatoid arthritis; Open label; Randomized controlled trial; Methotrexate; Internal medicine; Adalimumab","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004653214,0.0006518268,0.002655189,0.0003717002,0.0005004585,0.001075285,0.001003981,0.003509697,0.006959876],"category_scores_gemma":[0.005574237,0.0006671428,0.002176541,0.000594129,0.0008801822,0.001547742,0.0003025915,0.003628564,0.001558399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004915347,"about_ca_system_score_gemma":0.0006460958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009364536,"about_ca_topic_score_gemma":0.001713821,"domain_scores_codex":[0.9967393,0.001956875,0.0004266913,0.000325868,0.0003326715,0.0002184949],"domain_scores_gemma":[0.9963288,0.001742661,0.0008335627,0.0003411497,0.0002648594,0.0004890527],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8950508,0.009329146,0.002677976,0.001529757,0.00519061,0.0001459174,0.00006530369,0.0002543069,0.005783706,0.0001438146,0.00228698,0.07754169],"study_design_scores_gemma":[0.9068404,0.07601176,0.01166607,0.000198709,0.002758594,0.00009308418,0.00002752524,0.0003009446,0.0008254741,0.00009927384,0.001145514,0.00003249141],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9159811,0.06044758,0.001606247,0.004101966,0.001863093,0.003513109,0.00374465,0.0002560201,0.008486317],"genre_scores_gemma":[0.9792616,0.006611885,0.00255206,0.003244452,0.0009604252,0.001688088,0.002251867,0.0000315618,0.003397975],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006959876,"threshold_uncertainty_score":0.02460885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05332466539000915,"score_gpt":0.3587771181349563,"score_spread":0.3054524527449471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}