{"id":"W2525826975","doi":"10.1091/mbc.e16-01-0029","title":"Tau antagonizes end-binding protein tracking at microtubule ends through a phosphorylation-dependent mechanism","year":2016,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pediatric Oncology Group","funders":"Centre National de la Recherche Scientifique; Agence Nationale de la Recherche","keywords":"Microtubule; Biology; Cell biology; Tau protein; Microtubule-associated protein; Phosphorylation; Plasma protein binding; Biophysics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002192211,0.0002619736,0.0002391478,0.00003779902,0.0001561525,0.000009952611,0.000541571,0.0003443962,0.00008248007],"category_scores_gemma":[0.0000487708,0.000171517,0.0002593937,0.00008067423,0.0002175821,0.000005698498,0.0004927866,0.0001011665,0.00002435689],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005478029,"about_ca_system_score_gemma":0.00007104124,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003027513,"about_ca_topic_score_gemma":0.00002901172,"domain_scores_codex":[0.9984569,0.000168486,0.000340079,0.0005160825,0.0001188657,0.0003995817],"domain_scores_gemma":[0.9989126,0.0000164926,0.0002742775,0.000666513,0.00008038073,0.0000497315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005300904,0.00006361545,0.0005589597,0.00002164678,0.00006922373,0.000003118952,0.00006495925,0.000003228924,0.9976254,0.0009069146,0.00007303161,0.0005568998],"study_design_scores_gemma":[0.0008127738,0.0001749328,0.00003938779,0.00004181108,0.00003593804,0.0000224796,0.00002233928,0.000002591649,0.9928589,0.000944244,0.00479891,0.0002457239],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9821661,0.0009559984,0.01507141,0.0002789662,0.0002444214,0.0004700822,0.0001078732,0.00001511359,0.000690008],"genre_scores_gemma":[0.9943567,0.0001871708,0.001757878,0.0001822886,0.000058221,0.00004575026,0.00006614932,0.00004321007,0.003302655],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01331353,"threshold_uncertainty_score":0.6994261,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007199223863493094,"score_gpt":0.2273340759356144,"score_spread":0.2201348520721213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}