{"id":"W2527003447","doi":"10.1159/000449381","title":"Pre-Implantation Genetic Screening Techniques: Implications for Clinical Prenatal Diagnosis","year":2016,"lang":"en","type":"review","venue":"Fetal Diagnosis and Therapy","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal Ottawa Mental Health Centre","funders":"","keywords":"Aneuploidy; Genetic testing; Medicine; In vitro fertilisation; Advanced maternal age; Obstetrics; Embryo transfer; Gynecology; Blastocyst; Cell-free fetal DNA; Pregnancy; Embryo; Prenatal diagnosis; Biology; Fetus; Genetics; Internal medicine; Gene; Chromosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001322648,0.0008711764,0.001637032,0.004246595,0.000316319,0.001309808,0.001140077,0.001461604,0.005371002],"category_scores_gemma":[0.003048874,0.0002607576,0.00072884,0.003922572,0.0008977652,0.001988155,0.0008014693,0.002308207,0.002143078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009354107,"about_ca_system_score_gemma":0.001780841,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001756575,"about_ca_topic_score_gemma":0.002283847,"domain_scores_codex":[0.9995403,0.000121952,0.00008228001,0.00006720316,0.0001589805,0.00002929931],"domain_scores_gemma":[0.9978036,0.001477218,0.0002112386,0.00004699564,0.0003701051,0.00009074228],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003614487,0.00004209739,0.0003176421,0.01846722,0.00008641077,0.0002838571,0.00007568465,0.0002567333,0.0004946165,0.003375012,0.02421028,0.9523543],"study_design_scores_gemma":[0.00001460261,0.00005809823,0.001718866,0.01447081,0.0001782886,0.00342851,0.0001644089,0.00009654208,0.0001984417,0.004422532,0.9752226,0.00002639991],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002588382,0.9991106,0.000054021,0.0003581379,0.00007234712,0.000001438711,0.000007671122,0.000003013124,0.0003669071],"genre_scores_gemma":[0.0003207481,0.9991447,0.0001379573,0.0001453672,0.00009945831,0.000002893903,0.00001342502,8.225921e-7,0.0001347294],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005371002,"threshold_uncertainty_score":0.01796782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1367938596611152,"score_gpt":0.4407103119029646,"score_spread":0.3039164522418494,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}