{"id":"W2527203520","doi":"10.1016/j.chest.2016.09.012","title":"Biomarker Development in COPD","year":2016,"lang":"en","type":"review","venue":"CHEST Journal","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"Vancouver Coastal Health; Vancouver Coastal Health Research Institute; University of British Columbia; St. Paul's Hospital; Prevention of Organ Failure","funders":"Canadian Institutes of Health Research","keywords":"Biomarker; Medicine; Biomarker discovery; Precision medicine; Population; Translational research; Intensive care medicine; Bioinformatics; Pathology; Proteomics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004132671,0.00159484,0.004696277,0.004773924,0.0004176071,0.002722302,0.001440055,0.002322116,0.002867728],"category_scores_gemma":[0.006652119,0.0007867953,0.002577967,0.00377456,0.0008223868,0.002525768,0.001837527,0.002715838,0.0008999157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001016858,"about_ca_system_score_gemma":0.003379658,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001914926,"about_ca_topic_score_gemma":0.003597043,"domain_scores_codex":[0.9984981,0.0004237744,0.0003588519,0.0002098659,0.0004250311,0.00008431562],"domain_scores_gemma":[0.9966287,0.002264187,0.0004869357,0.00006548902,0.0004649626,0.00008957778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001620915,0.00007038079,0.0009835771,0.07828479,0.0009607513,0.0001617817,0.00008564528,0.0002138417,0.0005826135,0.002397766,0.01299429,0.9031026],"study_design_scores_gemma":[0.0002539314,0.0005329221,0.007074052,0.1352237,0.006964081,0.002904786,0.0003669564,0.0005760487,0.001473516,0.008624879,0.8358628,0.0001423888],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004267734,0.9995475,0.00005534288,0.0001410077,0.0001014375,0.000004326348,0.000009411255,0.000001791831,0.00009658332],"genre_scores_gemma":[0.00062671,0.9986802,0.0001868062,0.0002497701,0.0001409665,0.000008938029,0.00002209717,6.835378e-7,0.0000837826],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004773924,"threshold_uncertainty_score":0.02185595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0804738962710239,"score_gpt":0.3797314792626208,"score_spread":0.2992575829915969,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}