{"id":"W2527695830","doi":"10.3899/jrheum.160146","title":"Safety and Efficacy of SBI-087, a Subcutaneous Agent for B Cell Depletion, in Patients with Active Rheumatoid Arthritis: Results from a Phase II Randomized, Double-blind, Placebo-controlled Study","year":2016,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Pfizer","keywords":"Medicine; Rheumatoid arthritis; Placebo; Double blind; Randomized controlled trial; Arthritis; Placebo-controlled study; Surgery; Internal medicine; Alternative medicine; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001706561,0.001018285,0.002760435,0.0003807247,0.0003629018,0.0006516519,0.0008245179,0.001393163,0.003292058],"category_scores_gemma":[0.001193833,0.0005113878,0.001131283,0.0004137756,0.001006114,0.0006396024,0.0002198194,0.002073736,0.0009092049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003224414,"about_ca_system_score_gemma":0.0008954232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003508464,"about_ca_topic_score_gemma":0.0006638831,"domain_scores_codex":[0.9994596,0.000282696,0.00005271424,0.00007494034,0.00007695476,0.00005317543],"domain_scores_gemma":[0.9989917,0.0003024768,0.0002416715,0.00006699905,0.00008649706,0.0003107423],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8984094,0.02004479,0.002569282,0.001180718,0.001355637,0.00009724371,0.00008807518,0.0004038845,0.01846058,0.00006784589,0.0007672532,0.0565553],"study_design_scores_gemma":[0.7714196,0.2212362,0.004771295,0.00003335848,0.0005153406,0.00008360807,0.00002081878,0.0002995565,0.001020216,0.00003209501,0.0005549425,0.00001295642],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906173,0.005800148,0.0005386146,0.0002611435,0.0001396018,0.001271694,0.0004656416,0.0000808031,0.0008250952],"genre_scores_gemma":[0.9908365,0.003349785,0.001378404,0.0006723982,0.0003483645,0.001574583,0.0009374146,0.00001676386,0.0008858971],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003292058,"threshold_uncertainty_score":0.01101303,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01175034223159041,"score_gpt":0.2696767703390084,"score_spread":0.2579264281074179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}