{"id":"W2527743647","doi":"10.1038/srep30169","title":"Cranberry-derived proanthocyanidins impair virulence and inhibit quorum sensing of Pseudomonas aeruginosa","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":126,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Cranberry Institute","keywords":"Quorum sensing; Virulence; Pseudomonas aeruginosa; Biofilm; Microbiology; Biology; Bacteria; Drosophila melanogaster; Gene; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006566358,0.0001699697,0.0002017066,0.00006936054,0.0001846067,0.00007735714,0.00006569048,0.0001291114,0.00001527892],"category_scores_gemma":[0.0001808525,0.0001210736,0.00008550431,0.0001296631,0.000541022,0.00001553914,0.0001768176,0.00004246641,0.000003345157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001143801,"about_ca_system_score_gemma":0.0001216975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003058576,"about_ca_topic_score_gemma":0.00003837115,"domain_scores_codex":[0.9982486,0.00005049387,0.000424646,0.0007388359,0.0002041511,0.0003332862],"domain_scores_gemma":[0.9987836,0.00001237693,0.0002953401,0.0006166702,0.0001698032,0.000122134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002978036,0.00002101319,0.001833939,0.00001748897,0.00001474228,0.00004896881,0.00005314133,3.892942e-7,0.9892313,0.00001330602,0.0009029226,0.007833035],"study_design_scores_gemma":[0.000192953,0.00007519838,0.00180244,0.00009630889,0.00001304175,0.00048548,0.00003845237,0.000006385627,0.9864735,0.0001606342,0.01046678,0.0001888228],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971228,0.0001830761,0.0002372247,0.000262794,0.001684905,0.0001935598,0.000008547938,0.00001999236,0.0002870617],"genre_scores_gemma":[0.9974588,0.00003957601,0.001597994,0.00003038168,0.000110237,0.000001235155,0.00001902588,0.00001747376,0.0007252527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009563856,"threshold_uncertainty_score":0.4937238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00882209770802906,"score_gpt":0.2232023306703607,"score_spread":0.2143802329623316,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}