{"id":"W2527743647","doi":"10.1038/srep30169","title":"Cranberry-derived proanthocyanidins impair virulence and inhibit quorum sensing of Pseudomonas aeruginosa","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":126,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Cranberry Institute","keywords":"Quorum sensing; Virulence; Pseudomonas aeruginosa; Biofilm; Microbiology; Biology; Bacteria; Drosophila melanogaster; Gene; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001015032,0.0003581733,0.0001849832,0.0001110809,0.00008680397,0.0001604349,0.0001288102,0.0002046911,0.0004364032],"category_scores_gemma":[0.0001293335,0.00007168607,0.0001257282,0.00005260265,0.0002055103,0.0001355332,0.0001647631,0.0003355388,0.00009254955],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001876381,"about_ca_system_score_gemma":0.0002029993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007897294,"about_ca_topic_score_gemma":0.001303761,"domain_scores_codex":[0.999881,0.00002348779,0.000007176308,0.000016558,0.00004466139,0.00002706087],"domain_scores_gemma":[0.9998932,0.00001848096,0.00003614355,0.00001200044,0.00001248581,0.00002772263],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004377582,0.00001313335,0.00008037588,0.00001658027,0.000002269744,0.00001326454,0.000003486228,0.00001835741,0.9992912,0.00002029145,0.00001088699,0.0004865323],"study_design_scores_gemma":[0.00001216407,0.0002570822,0.006327311,0.000004019967,0.000008835057,0.0001006217,0.00001266186,0.0004770955,0.991912,0.00001887231,0.000866978,0.000002275267],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972179,0.001561498,0.0005780922,0.00007185526,0.000007729583,0.000008442973,0.00006746096,0.00002453665,0.0004625183],"genre_scores_gemma":[0.9969983,0.0006949494,0.001089506,0.0000386061,0.000004338223,0.00001172101,0.0001292835,0.000008054152,0.001025252],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007897294,"threshold_uncertainty_score":0.001570225,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00882209770802906,"score_gpt":0.2232023306703607,"score_spread":0.2143802329623316,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}