{"id":"W2527826685","doi":"10.1182/blood-2016-08-729517","title":"B cells, PF4/heparin complexes, and complement","year":2016,"lang":"en","type":"letter","venue":"Blood","topic":"Heparin-Induced Thrombocytopenia and Thrombosis","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Complement system; Heparin; Platelet factor 4; Alternative complement pathway; Factor H; Complement (music); Complement receptor; Platelet; Chemistry; Receptor; Platelet activation; Cell biology; Immunology; Biology; Biochemistry; Antibody; Phenotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007812708,0.001013967,0.0008590242,0.0006513445,0.001301557,0.002390683,0.001107843,0.01265532,0.008577879],"category_scores_gemma":[0.004406068,0.0004651412,0.0005412522,0.0004750549,0.001600541,0.002240677,0.0006332624,0.01176237,0.006129871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001964067,"about_ca_system_score_gemma":0.001147113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009651671,"about_ca_topic_score_gemma":0.00200454,"domain_scores_codex":[0.9987388,0.0004109996,0.0001305469,0.0001570426,0.0004386135,0.0001240887],"domain_scores_gemma":[0.9988472,0.0005677703,0.0001312804,0.00005937391,0.0001985153,0.000195815],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001211135,0.0001200787,0.001256883,0.0001951598,0.00002894122,0.01390615,0.00007024916,0.00007441908,0.0006044257,0.003626587,0.934907,0.04508902],"study_design_scores_gemma":[0.0001914256,0.0001877395,0.001996149,0.0003535527,0.00004178793,0.02723474,0.0001811847,0.0004009983,0.0005482424,0.008566938,0.9602682,0.00002898712],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.002934647,0.0395535,0.0004736303,0.7965986,0.1367576,0.00004844903,0.00006972708,0.0001399874,0.02342387],"genre_scores_gemma":[0.019121,0.02315462,0.0005209305,0.3424228,0.5941211,0.00004289651,0.00007517516,0.00003329946,0.02050823],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01265532,"threshold_uncertainty_score":0.02869588,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0404370857114142,"score_gpt":0.276892381644386,"score_spread":0.2364552959329718,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}