{"id":"W2527838981","doi":"10.1021/acs.analchem.6b02298","title":"Imaging Taurine in the Central Nervous System Using Chemically Specific X-ray Fluorescence Imaging at the Sulfur K-Edge","year":2016,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Aldose Reductase and Taurine","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; National Institute of General Medical Sciences; Canada Research Chairs; Saskatchewan Health Research Foundation; Heart and Stroke Foundation of Canada","keywords":"Chemistry; Fluorescence; Sulfur; Central nervous system; X-ray; X-ray fluorescence; Fluorescence-lifetime imaging microscopy; Optics; Neuroscience; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002882584,0.0002627535,0.0002026899,0.00001588969,0.0001438612,0.00005487786,0.0005565193,0.00008652497,0.00008950738],"category_scores_gemma":[0.00008513463,0.0001399022,0.0001668229,0.0001677826,0.000355784,0.000009208745,0.0002852053,0.0001787615,0.00002200433],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001534009,"about_ca_system_score_gemma":0.00007895619,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003156183,"about_ca_topic_score_gemma":0.000003189085,"domain_scores_codex":[0.9981428,0.0000551836,0.0003538995,0.0005394183,0.0002751609,0.0006335432],"domain_scores_gemma":[0.9989111,0.00005760048,0.00009169781,0.0007461332,0.00006388935,0.0001296028],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005090617,0.0000474011,0.008542606,0.00004344565,0.00002667931,0.0001250119,0.00002010509,0.00001044996,0.9877218,0.00004658261,0.002136229,0.001228766],"study_design_scores_gemma":[0.0008640218,0.00001099552,0.004851897,0.0001633873,0.0000729747,0.000715694,0.0004311814,0.001480139,0.9721906,0.00002779797,0.01874319,0.0004480815],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937528,0.001169787,0.0003972735,0.001752883,0.00006446314,0.0001303249,0.00002441202,0.00001951941,0.002688571],"genre_scores_gemma":[0.9982432,0.00009923533,0.00008338939,0.0001725412,0.0007619718,0.000009451889,0.00005123332,0.00002769949,0.000551341],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01660696,"threshold_uncertainty_score":0.5705045,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009255960395140487,"score_gpt":0.2313536048275843,"score_spread":0.2220976444324438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}