{"id":"W2528460956","doi":"10.1097/moh.0000000000000296","title":"Primary immunodeficiencies due to abnormalities of the actin cytoskeleton","year":2016,"lang":"en","type":"review","venue":"Current Opinion in Hematology","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Wellcome Trust","keywords":"Biology; Cytoskeleton; Actin cytoskeleton; Actin; Cell biology; Immune system; Immunology; Intracellular; Phenotype; Cell; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005771409,0.0005986612,0.002514261,0.0005234842,0.0002119916,0.00001178929,0.001505117,0.0006735296,0.0002408948],"category_scores_gemma":[0.0002919195,0.0003641794,0.000714838,0.0006790114,0.0007343307,0.00009243419,0.0007479159,0.0008794507,0.0005800073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001484724,"about_ca_system_score_gemma":0.0006046603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003438479,"about_ca_topic_score_gemma":7.708925e-7,"domain_scores_codex":[0.9959303,0.0009443103,0.001639821,0.0005934871,0.00009833174,0.000793752],"domain_scores_gemma":[0.9972726,0.0007334672,0.0008610567,0.001040884,0.00008221347,0.000009807181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003590941,0.0003152382,0.00003511382,0.02015034,0.0001065523,7.693284e-7,0.0007279034,7.529813e-7,0.0001099643,0.01381103,0.001137746,0.9635687],"study_design_scores_gemma":[0.0004064803,0.00005321937,0.0001173639,0.02546025,0.00005050601,0.0003524827,0.0001658785,4.825387e-8,0.0001381678,0.0001292533,0.9727175,0.000408799],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000157167,0.9814752,0.0000607059,0.0001012642,0.01639209,0.001066491,0.0001353225,0.00004718294,0.000564575],"genre_scores_gemma":[0.001130868,0.9979578,0.000003885438,0.00001922854,0.00001411919,0.0002947108,0.000165025,0.00004303887,0.0003712866],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9715798,"threshold_uncertainty_score":0.999881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05035194859640195,"score_gpt":0.3366719445202673,"score_spread":0.2863199959238653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}