{"id":"W2528494739","doi":"10.1186/s12934-016-0568-6","title":"Enzymatic fine-tuning for 2-(6-hydroxynaphthyl) β-d-xylopyranoside synthesis catalyzed by the recombinant β-xylosidase BxTW1 from Talaromyces amestolkiae","year":2016,"lang":"en","type":"article","venue":"Microbial Cell Factories","topic":"Biofuel production and bioconversion","field":"Engineering","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Instituto de Salud Carlos III; Ministerio de Economía y Competitividad; Comunidad de Madrid","keywords":"Pichia pastoris; Aglycone; Chemistry; Enzyme; Pichia; Yeast; Glycoside hydrolase; Glycoside; Biochemistry; Glycan; Stereochemistry; Glycosylation; Recombinant DNA; Gene; Glycoprotein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001347805,0.0003381759,0.000321879,0.00006298931,0.0002784019,0.0001001912,0.0003462484,0.0001828071,0.0003302359],"category_scores_gemma":[0.00007982332,0.0002026765,0.0001609943,0.0001263844,0.0001692939,0.0002468709,0.00006175582,0.0001416308,0.0001150044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001158406,"about_ca_system_score_gemma":0.0000262492,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002129896,"about_ca_topic_score_gemma":0.00003527416,"domain_scores_codex":[0.9986714,0.00005829291,0.0003521647,0.0003742853,0.0001296896,0.0004142089],"domain_scores_gemma":[0.998873,0.0004754866,0.00009701208,0.0004154273,0.00004656954,0.00009247947],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004144976,0.00003272318,0.0001521132,0.000148668,0.0000519101,0.000001564931,0.0003323157,0.000004947731,0.9438521,0.000005367192,0.05394128,0.001435577],"study_design_scores_gemma":[0.0005341723,0.00002769438,0.00005579128,0.00008122186,0.00005983577,0.000004010473,0.0001485334,0.00007307358,0.8797175,0.0001080582,0.1188576,0.0003325247],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902935,0.00130299,0.002630414,0.0015414,0.002378822,0.0005578632,0.0007129659,0.0003956138,0.0001864247],"genre_scores_gemma":[0.9975575,0.0001925127,0.0003531235,0.00004937921,0.0001936114,0.00006676928,0.0001046761,0.00006129382,0.001421109],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06491631,"threshold_uncertainty_score":0.8264907,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007869459951412786,"score_gpt":0.1793331507190628,"score_spread":0.17146369076765,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}