{"id":"W2528494739","doi":"10.1186/s12934-016-0568-6","title":"Enzymatic fine-tuning for 2-(6-hydroxynaphthyl) β-d-xylopyranoside synthesis catalyzed by the recombinant β-xylosidase BxTW1 from Talaromyces amestolkiae","year":2016,"lang":"en","type":"article","venue":"Microbial Cell Factories","topic":"Biofuel production and bioconversion","field":"Engineering","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Instituto de Salud Carlos III; Ministerio de Economía y Competitividad; Comunidad de Madrid","keywords":"Pichia pastoris; Aglycone; Chemistry; Enzyme; Pichia; Yeast; Glycoside hydrolase; Glycoside; Biochemistry; Glycan; Stereochemistry; Glycosylation; Recombinant DNA; Gene; Glycoprotein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001922581,0.0004260815,0.0002005285,0.0001672649,0.0000726129,0.0002813108,0.0001936494,0.000213868,0.0005005811],"category_scores_gemma":[0.0001543044,0.00008838724,0.0002465251,0.0002078377,0.0001486416,0.00020496,0.0002069798,0.0004778413,0.0003460888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000181301,"about_ca_system_score_gemma":0.000141712,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002795903,"about_ca_topic_score_gemma":0.000371126,"domain_scores_codex":[0.9998574,0.00002140915,0.00001502031,0.00003538133,0.00004696818,0.00002383337],"domain_scores_gemma":[0.9999394,0.00001233488,0.00002047499,0.000008861019,0.00001078138,0.000008123321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001309328,0.00001164207,0.00005028398,0.00002249315,0.000001824009,0.00001367543,0.000006007008,0.00006252556,0.998949,0.00002583677,0.000008056953,0.0008356155],"study_design_scores_gemma":[0.000002260026,0.00006002889,0.0005134206,0.000002427695,0.000005357178,0.00005645063,0.00000804942,0.0005027545,0.9980208,0.00001572448,0.0008102247,0.000002616991],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9791443,0.001398907,0.01735967,0.0001035855,0.00002448231,0.00005633223,0.0003330704,0.0001295418,0.001450024],"genre_scores_gemma":[0.9840723,0.001078904,0.01312277,0.00002792963,0.000007774832,0.00004901764,0.0004980188,0.00003787869,0.001105386],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005005811,"threshold_uncertainty_score":0.001674652,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007869459951412786,"score_gpt":0.1793331507190628,"score_spread":0.17146369076765,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}