{"id":"W2528802029","doi":"10.1101/078477","title":"Human enhancers harboring specific sequence composition, activity, and genome organization are linked to the immune response","year":2016,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute","funders":"","keywords":"Enhancer; Chromatin; Gene; Enhancer RNAs; Genome; Human genome; Regulation of gene expression; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001804742,0.0001389094,0.0001853805,0.0004465935,0.0001185879,0.0001976111,0.00008557053,0.000187385,0.002073682],"category_scores_gemma":[0.0003358599,0.0001377395,0.0001848542,0.0002599249,0.0001188813,0.00007665646,0.0001590332,0.0002295873,0.0003866006],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001064135,"about_ca_system_score_gemma":0.00007608935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005273565,"about_ca_topic_score_gemma":0.0008111069,"domain_scores_codex":[0.9998997,0.00001319512,0.000005210393,0.00004146214,0.0000184012,0.00002195516],"domain_scores_gemma":[0.9997926,0.00008879813,0.00004536861,0.00002539479,0.00002288933,0.00002486028],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000748647,0.00003224768,0.03673554,0.0001660753,0.00005957209,0.0002843715,0.0001524294,0.000285686,0.9488335,0.00050688,0.0002521329,0.01194271],"study_design_scores_gemma":[0.00004262787,0.0001409943,0.7669961,0.00004123389,0.000106232,0.002607648,0.0000889814,0.001716496,0.2203185,0.0009410331,0.006976698,0.00002349759],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907156,0.00152795,0.003961883,0.00005554453,0.0000105533,0.000008942471,0.002047116,0.00008672314,0.001585646],"genre_scores_gemma":[0.9934633,0.0002633895,0.002316335,0.00005778748,0.00001188371,0.000009676488,0.002762778,0.00002423901,0.001090686],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002073682,"threshold_uncertainty_score":0.006937146,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01070070752787757,"score_gpt":0.2197284171998112,"score_spread":0.2090277096719336,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}