{"id":"W2528935869","doi":"","title":"The role of the tumor microenvironment: The matricellular protein CCN2/CTGF is essential for melanoma metastasis","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical & Experimental Dermatology Research","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Periostin; Matricellular protein; Melanoma; Cancer research; CTGF; Stromal cell; Metastasis; Medicine; Stroma; Cancer; Pathology; Tumor microenvironment; Extracellular matrix; Growth factor; Biology; Internal medicine; Immunohistochemistry; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001073618,0.0003473127,0.0001230329,0.000199488,0.0003102101,0.0004091511,0.0001604518,0.0002930762,0.000857611],"category_scores_gemma":[0.0001586166,0.00009674098,0.0001137312,0.00009021369,0.0002458765,0.0002416515,0.0003305688,0.0002907443,0.0002239226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004304139,"about_ca_system_score_gemma":0.000433609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002125819,"about_ca_topic_score_gemma":0.002420764,"domain_scores_codex":[0.999878,0.00002373666,0.000007288352,0.0000229417,0.00004085536,0.00002705277],"domain_scores_gemma":[0.9998698,0.000007893248,0.00003984442,0.000008217886,0.00001861407,0.00005569939],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006910703,0.00001368574,0.001933226,0.00008124678,0.000006210291,0.0002648345,0.00002252658,0.0001177015,0.9931428,0.0004704367,0.0002407926,0.003637419],"study_design_scores_gemma":[0.00004285203,0.0004926673,0.1845035,0.00008310467,0.0000541308,0.005861758,0.0002116562,0.005760905,0.7691104,0.0008696427,0.03297675,0.00003272477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9679161,0.02080011,0.005127845,0.0008542447,0.00008161169,0.00005339587,0.0005664871,0.0001916318,0.004408612],"genre_scores_gemma":[0.994843,0.002501112,0.00102896,0.00005523411,0.00001906005,0.00001966509,0.0001678584,0.000009227166,0.001355745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002125819,"threshold_uncertainty_score":0.004226863,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0484417924395793,"score_gpt":0.4201019403577508,"score_spread":0.3716601479181715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}