{"id":"W2528935869","doi":"","title":"The role of the tumor microenvironment: The matricellular protein CCN2/CTGF is essential for melanoma metastasis","year":2016,"lang":"en","type":"article","venue":"Journal of Clinical & Experimental Dermatology Research","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Periostin; Matricellular protein; Melanoma; Cancer research; CTGF; Stromal cell; Metastasis; Medicine; Stroma; Cancer; Pathology; Tumor microenvironment; Extracellular matrix; Growth factor; Biology; Internal medicine; Immunohistochemistry; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003238738,0.0001617409,0.0003949466,0.000062929,0.0004460262,0.0000402972,0.001481107,0.0001557933,0.0001071931],"category_scores_gemma":[0.001613213,0.0000676166,0.0005899533,0.00014567,0.001813793,0.00001336818,0.0007891738,0.0005041873,0.00001673258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004079148,"about_ca_system_score_gemma":0.0002942836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001224502,"about_ca_topic_score_gemma":0.000006052066,"domain_scores_codex":[0.9953943,0.001907202,0.001077787,0.0003049576,0.0007644948,0.000551198],"domain_scores_gemma":[0.9969568,0.001335499,0.0005179131,0.0006689694,0.0003722738,0.000148519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001385308,0.0002864047,0.009600905,0.000011599,0.0003191503,0.00001218068,0.0000608368,1.197771e-7,0.9816517,0.0003767989,0.003120097,0.003174911],"study_design_scores_gemma":[0.001337121,0.0006828235,0.001758395,0.00002387242,0.00002188051,0.0002264796,0.0005666062,0.000006627171,0.8698372,0.0006073874,0.1248586,0.00007308747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9811209,0.009737026,0.0001024833,0.00779738,0.0001815557,0.0008940532,0.00003834351,0.000001527064,0.0001267665],"genre_scores_gemma":[0.9986153,0.0002918194,0.0001094607,0.00008701588,0.0002824801,0.00009045481,0.000001246855,0.00002666045,0.000495589],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1217385,"threshold_uncertainty_score":0.6682995,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0484417924395793,"score_gpt":0.4201019403577508,"score_spread":0.3716601479181715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}