{"id":"W2529022019","doi":"10.1128/jvi.01563-16","title":"The Tetherin Antagonism of the Ebola Virus Glycoprotein Requires an Intact Receptor-Binding Domain and Can Be Blocked by GP1-Specific Antibodies","year":2016,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada","funders":"","keywords":"Ebola virus; Tetherin; Virology; Filoviridae; Biology; Ebolavirus; VP40; Glycoprotein; Virus; Viral replication; Molecular biology; Viral disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001542839,0.0005710682,0.0003862803,0.0002400413,0.0001973411,0.0002957503,0.0004995757,0.0005290169,0.002409747],"category_scores_gemma":[0.0001759129,0.0002254114,0.0004893827,0.0001559575,0.0002866075,0.0002668814,0.0002814067,0.001147074,0.0005997925],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005498957,"about_ca_system_score_gemma":0.0003124507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008978051,"about_ca_topic_score_gemma":0.001470107,"domain_scores_codex":[0.9996177,0.00006151033,0.00002887763,0.00005261007,0.00009960822,0.0001396412],"domain_scores_gemma":[0.9998362,0.00006141861,0.00002447284,0.00002941259,0.00001698197,0.00003153522],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006591686,0.00005181967,0.00006128467,0.00002804848,0.000005178052,0.00004314815,0.000009675517,0.00002749923,0.9990848,0.000100647,0.00001935193,0.0005026844],"study_design_scores_gemma":[0.00004336144,0.000442797,0.006184896,0.000007841682,0.00002125038,0.0004173718,0.00001687295,0.0009221168,0.9888499,0.0000518288,0.003036473,0.000005225475],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934488,0.001357662,0.001509225,0.00008807563,0.00003598139,0.00004902119,0.000181889,0.00003845046,0.003290898],"genre_scores_gemma":[0.9919539,0.001169652,0.001715418,0.00008494847,0.00002033602,0.00008973083,0.0007205541,0.00002792938,0.004217556],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002409747,"threshold_uncertainty_score":0.008061409,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02124740057883911,"score_gpt":0.304570859287179,"score_spread":0.2833234587083399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}