{"id":"W2529079515","doi":"10.1038/cddiscovery.2016.72","title":"P53 regulates disruption of neuronal development in the adult hippocampus after irradiation","year":2016,"lang":"en","type":"article","venue":"Cell Death Discovery","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"Canadian Cancer Society Research Institute; Cancer Research Society","keywords":"Neurogenesis; Neural stem cell; Neuroblast; Hippocampal formation; Biology; Progenitor cell; Hippocampus; Bromodeoxyuridine; Stem cell; Cell biology; Apoptosis; Transplantation; Neuroscience; Programmed cell death; DNA damage; Cell growth; Internal medicine; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007809532,0.0002378597,0.0001881164,0.0003105039,0.0001067372,0.0001994015,0.0001406571,0.0002139308,0.0007108242],"category_scores_gemma":[0.00008245225,0.00009828949,0.0001502066,0.00009103605,0.0002620481,0.0001602268,0.0001624353,0.0003497731,0.0001729138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001944494,"about_ca_system_score_gemma":0.00009049207,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003149084,"about_ca_topic_score_gemma":0.0004118783,"domain_scores_codex":[0.9999268,0.00001141218,0.000006932378,0.00001597204,0.00001666832,0.0000222551],"domain_scores_gemma":[0.9999294,0.000009121105,0.00003019489,0.000006606819,0.000009218199,0.00001545262],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007084677,0.0000110803,0.0002692917,0.00001158775,0.000003199312,0.0000862189,0.000008432769,0.00001783526,0.9988493,0.00003840989,0.00001127026,0.0006225411],"study_design_scores_gemma":[0.000007283668,0.000254804,0.01446132,0.000007431662,0.00001606817,0.0004107004,0.00003874402,0.0002589826,0.9839352,0.00007780635,0.0005291014,0.000002534739],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961103,0.00188905,0.001266605,0.00003118287,0.00001000241,0.000007790813,0.0001212352,0.00004734946,0.0005165375],"genre_scores_gemma":[0.9973935,0.0009178066,0.0005239134,0.00001380357,0.000003047073,0.0000137896,0.0001173369,0.000008341408,0.001008508],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007108242,"threshold_uncertainty_score":0.002377927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01850652325681848,"score_gpt":0.2241379168769801,"score_spread":0.2056313936201616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}