{"id":"W2529223014","doi":"10.1016/j.virol.2016.09.021","title":"Pathogenic infection of Rhesus macaques by an evolving SIV-HIV derived from CCR5-using envelope genes of acute HIV-1 infections","year":2016,"lang":"en","type":"article","venue":"Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Biology; Virology; Simian immunodeficiency virus; Gp41; Macaque; Virus; Rhesus macaque; Pathogenesis; Immune system; Lentivirus; Viral pathogenesis; Phenotype; Gene; Heptad repeat; Immunology; Antibody; Viral replication; Viral disease; Genetics; Peptide sequence; Epitope","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001119285,0.0001664762,0.0003595392,0.0001777264,0.0001337726,0.000004381402,0.0001216067,0.000300756,0.001064974],"category_scores_gemma":[0.00006903386,0.0001225231,0.0001003878,0.0001069701,0.0003775572,0.0001505935,0.00009309327,0.0001225253,0.0003042189],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005892631,"about_ca_system_score_gemma":0.00009047026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001230093,"about_ca_topic_score_gemma":0.0002436492,"domain_scores_codex":[0.9985311,0.000454643,0.000322193,0.0003055746,0.00003494367,0.0003515586],"domain_scores_gemma":[0.9991475,0.0002324417,0.0001770547,0.0002923449,0.0001100693,0.00004062259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000147417,0.0002701658,0.1385103,0.000005168485,0.0006406157,0.000007117891,0.0001339822,0.000002763036,0.8538843,0.00002200994,0.0002733835,0.006102713],"study_design_scores_gemma":[0.00240261,0.001033436,0.2841488,0.00002607851,0.0002247656,0.00007909791,0.00002150662,0.00001406921,0.7091706,0.0002696085,0.00243961,0.0001698277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921189,0.001662124,0.004451656,0.0001190234,0.0002015564,0.0001779499,0.00112683,0.00004606134,0.000095904],"genre_scores_gemma":[0.99795,0.001019814,0.0003129569,0.00002040109,0.00002612947,0.0000284086,0.0004393744,0.00001753034,0.0001854031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1456385,"threshold_uncertainty_score":0.9998482,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01457128129041809,"score_gpt":0.2645640702467872,"score_spread":0.2499927889563691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}