{"id":"W2529223014","doi":"10.1016/j.virol.2016.09.021","title":"Pathogenic infection of Rhesus macaques by an evolving SIV-HIV derived from CCR5-using envelope genes of acute HIV-1 infections","year":2016,"lang":"en","type":"article","venue":"Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Biology; Virology; Simian immunodeficiency virus; Gp41; Macaque; Virus; Rhesus macaque; Pathogenesis; Immune system; Lentivirus; Viral pathogenesis; Phenotype; Gene; Heptad repeat; Immunology; Antibody; Viral replication; Viral disease; Genetics; Peptide sequence; Epitope","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000208029,0.0002011025,0.0001693941,0.0002201483,0.0004626854,0.0004272578,0.0001769812,0.0002640676,0.0008152568],"category_scores_gemma":[0.0003371024,0.0001068296,0.0001470434,0.00007877385,0.0003136685,0.0001606089,0.0002200274,0.0005287344,0.0001678239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002747418,"about_ca_system_score_gemma":0.0002175608,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002006801,"about_ca_topic_score_gemma":0.001939102,"domain_scores_codex":[0.9998828,0.00002498784,0.000006269443,0.0000200564,0.00001696261,0.00004888152],"domain_scores_gemma":[0.9999057,0.00002287016,0.00001437342,0.00001585969,0.00001366645,0.00002744398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004442061,0.0001114671,0.006352867,0.00002295177,0.00001051309,0.0006882236,0.0003117596,0.00007523745,0.9886233,0.0004916899,0.00005773355,0.002810152],"study_design_scores_gemma":[0.000161979,0.004621807,0.287144,0.00008915267,0.0002000841,0.01977407,0.002007267,0.0075015,0.6690996,0.001688115,0.007653054,0.00005933187],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996632,0.00004850901,0.00007755586,0.000007841175,0.000002883661,0.000004774823,0.00001207321,0.000002384857,0.0001807982],"genre_scores_gemma":[0.9990583,0.00007579919,0.0003141271,0.00002562668,0.000004374623,0.000008836585,0.00008077613,0.000004332949,0.000427742],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002006801,"threshold_uncertainty_score":0.003990293,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01457128129041809,"score_gpt":0.2645640702467872,"score_spread":0.2499927889563691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}