{"id":"W2529301266","doi":"10.1080/19382014.2016.1243191","title":"The P21-activated kinase PAK4 is implicated in fatty-acid potentiation of insulin secretion downstream of free fatty acid receptor 1","year":2016,"lang":"en","type":"article","venue":"Islets","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Diabetes Canada","funders":"Canadian Institutes of Health Research","keywords":"Free fatty acid receptor 1; Long-term potentiation; Free fatty acid receptor; Fatty acid; Secretion; Insulin; Insulin receptor; Phosphorylation; Biology; Gene knockdown; Kinase; Cell biology; Internal medicine; Receptor; Endocrinology; Biochemistry; Insulin resistance; Medicine; Polyunsaturated fatty acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000227986,0.0001387504,0.0002980549,0.0001192032,0.00004153823,0.000006385952,0.0001111623,0.0001358969,0.0005306159],"category_scores_gemma":[0.0007280071,0.00008146317,0.00008734011,0.0003387438,0.0001159497,0.00009517987,0.00003887209,0.00009371187,0.00004871691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008024518,"about_ca_system_score_gemma":0.00006265363,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001167831,"about_ca_topic_score_gemma":0.000005394106,"domain_scores_codex":[0.998796,0.00008381478,0.000448837,0.0002151768,0.0002527422,0.0002034006],"domain_scores_gemma":[0.9987976,0.0001387416,0.0002658177,0.0005084872,0.0002123545,0.00007700697],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005344041,0.000161666,0.01180157,0.00003854261,0.00005191074,0.000001273635,0.0001332986,4.817774e-7,0.9576051,0.00004867215,0.00156754,0.02805559],"study_design_scores_gemma":[0.002799049,0.0002737997,0.09684539,0.0002169027,0.00003567518,0.000002290947,0.00007752512,0.00005067856,0.8981478,0.0002305309,0.001238134,0.00008228511],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944351,0.0002214823,0.0007929907,0.002980349,0.0001749646,0.0003487428,0.0001010045,0.000044552,0.000900781],"genre_scores_gemma":[0.9990484,0.0002067954,0.0002788237,0.0001897513,0.00004732662,0.00003274109,0.00006302273,0.0000153796,0.0001178234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08504382,"threshold_uncertainty_score":0.5809872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01343792531144713,"score_gpt":0.2446325403860844,"score_spread":0.2311946150746372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}