{"id":"W2529301266","doi":"10.1080/19382014.2016.1243191","title":"The P21-activated kinase PAK4 is implicated in fatty-acid potentiation of insulin secretion downstream of free fatty acid receptor 1","year":2016,"lang":"en","type":"article","venue":"Islets","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Diabetes Canada","funders":"Canadian Institutes of Health Research","keywords":"Free fatty acid receptor 1; Long-term potentiation; Free fatty acid receptor; Fatty acid; Secretion; Insulin; Insulin receptor; Phosphorylation; Biology; Gene knockdown; Kinase; Cell biology; Internal medicine; Receptor; Endocrinology; Biochemistry; Insulin resistance; Medicine; Polyunsaturated fatty acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001315394,0.0005246771,0.000270433,0.0004009429,0.0004821362,0.00040792,0.0001953121,0.0003137328,0.001845269],"category_scores_gemma":[0.0001518878,0.000211452,0.0005151024,0.0003012363,0.0002866706,0.000360797,0.0004631937,0.0005945165,0.0005777687],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002537017,"about_ca_system_score_gemma":0.0002263523,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002611116,"about_ca_topic_score_gemma":0.0002670214,"domain_scores_codex":[0.9998963,0.0000209427,0.000009199767,0.00001700411,0.00001765009,0.00003887609],"domain_scores_gemma":[0.9999157,0.000005959524,0.00004043061,0.000007143808,0.000009210567,0.00002153112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001450131,0.0000959676,0.002372779,0.0003041377,0.00005213082,0.001085707,0.00005042819,0.0002733344,0.9872798,0.0006604639,0.0003602343,0.006015017],"study_design_scores_gemma":[0.0002138887,0.0006925305,0.09707964,0.00005050189,0.0002466284,0.003668482,0.0002291391,0.003411631,0.8790293,0.001441705,0.01390257,0.0000339394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863919,0.007285863,0.002270398,0.0004362364,0.00007276256,0.00002625091,0.0003126667,0.00009881787,0.003105146],"genre_scores_gemma":[0.9916131,0.004290209,0.001092767,0.00006604212,0.00002360342,0.00003470792,0.0004251488,0.00001401682,0.002440359],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001845269,"threshold_uncertainty_score":0.006173015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01343792531144713,"score_gpt":0.2446325403860844,"score_spread":0.2311946150746372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}