{"id":"W2529512895","doi":"10.1039/c6ob01718e","title":"Effect of novel triazole–amino acid hybrids on growth and virulence of Candida species: in vitro and in vivo studies","year":2016,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Genome Canada","funders":"Royal Society of Chemistry; Royal Society","keywords":"Chemistry; In vivo; Virulence; In vitro; Hybrid; Triazole; Microbiology; Antifungal; Biochemistry; Biology; Genetics; Gene; Botany; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001170607,0.0003490638,0.0002702567,0.0001629494,0.0001136962,0.0001649061,0.0002211491,0.0002831217,0.001085425],"category_scores_gemma":[0.0000897287,0.00009529298,0.0002092002,0.0001568749,0.00008195441,0.0001018325,0.00008903617,0.0003845094,0.0002522726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001761761,"about_ca_system_score_gemma":0.0001168852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001302508,"about_ca_topic_score_gemma":0.002077154,"domain_scores_codex":[0.9999188,0.00001697945,0.000006326982,0.00001231573,0.00002351069,0.00002211533],"domain_scores_gemma":[0.9999439,0.00001133661,0.00001266363,0.000004234947,0.000009106322,0.00001884363],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002281285,0.00009199057,0.00005704872,0.00004170161,0.00001480419,0.00004304096,0.00000904329,0.0001675064,0.9982656,0.0000218267,0.00004201117,0.001017472],"study_design_scores_gemma":[0.00002690298,0.001491668,0.00133722,0.000004009154,0.00003550049,0.0001486911,0.00001245141,0.0006178198,0.9952962,0.000007262644,0.001013894,0.000008328743],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961227,0.001909932,0.000548817,0.00005018165,0.00002605248,0.00002102056,0.0002566684,0.0000608214,0.001003872],"genre_scores_gemma":[0.9962521,0.001236778,0.0009653003,0.00003945383,0.000005970225,0.00001590793,0.0003637472,0.00001017666,0.00111054],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001302508,"threshold_uncertainty_score":0.003631115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009613424265082092,"score_gpt":0.2640314546881492,"score_spread":0.2544180304230671,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}