{"id":"W2529738115","doi":"10.1016/j.cllc.2016.09.002","title":"Phase 1/2 Study of the CD56-Targeting Antibody-Drug Conjugate Lorvotuzumab Mertansine (IMGN901) in Combination With Carboplatin/Etoposide in Small-Cell Lung Cancer Patients With Extensive-Stage Disease","year":2016,"lang":"en","type":"article","venue":"Clinical Lung Cancer","topic":"Lung Cancer Research Studies","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"Juravinski Cancer Centre","funders":"ImmunoGen","keywords":"Carboplatin; Medicine; Etoposide; Internal medicine; Adverse effect; Phases of clinical research; Lung cancer; Gastroenterology; Chemotherapy; Surgery; Cisplatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007082772,0.0003920636,0.0009843373,0.0001724915,0.0001202423,0.0000190414,0.0002875862,0.00008296882,0.00007751091],"category_scores_gemma":[0.0006996221,0.0002016245,0.0001117034,0.0007249568,0.0004616627,0.0001843372,0.0002145388,0.0005972188,0.000001056108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009110695,"about_ca_system_score_gemma":0.001106012,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003720379,"about_ca_topic_score_gemma":0.01072918,"domain_scores_codex":[0.9960976,0.0004342225,0.001137319,0.0008444797,0.0008525483,0.0006338887],"domain_scores_gemma":[0.9968776,0.0007436826,0.000577101,0.0006435887,0.0008656226,0.0002924585],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.008318297,0.004881216,0.9822566,0.0005767235,0.0003246528,0.0001169873,0.001188713,0.0002361587,0.0004243677,0.00001272749,0.0004483189,0.001215277],"study_design_scores_gemma":[0.06630426,0.002032696,0.9237058,0.003519702,0.0005775075,2.98372e-7,0.0005338217,0.002434774,0.0004443793,0.00001057828,0.00008472146,0.0003514659],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902647,0.002475627,0.00002711086,0.002097404,0.0003339101,0.004507214,0.000135464,0.00003347002,0.0001250907],"genre_scores_gemma":[0.9975053,0.0006538969,0.00003771365,0.0003718779,0.000130234,0.0005014447,0.00002019438,0.00007237266,0.0007069557],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05855076,"threshold_uncertainty_score":0.8222009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02302611129199081,"score_gpt":0.3965206617871,"score_spread":0.3734945504951092,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}